Results 51 to 60 of about 23,403,763 (259)

Dual Compartmentalization of GSTA4 Suppresses Ferroptosis to Drive Antiandrogen Resistance in Prostate Cancer

Advanced Science, EarlyView.
The schematic diagram depicts a compartmentalized anti‐ferroptotic defense mechanism mediated by GSTA4. GSTA4 is upregulated and localizes to the cytoplasm in ENZR cells, where it detoxifies 4‐HNE via a non‐canonical GSH‐dependent pathway. Under oxidative stress, GSTA4 translocates to mitochondria, interacts with PGAM5, and blocks Drp1 Ser637 ...
Yong Luo, Wei Zhuang, Zean Li, Yiming Lai, Yongyi Ou, Dongquan Li, Shanhe Huang, Tianlong Luo, Jintao Hu, Bingliang Chen, Jianhan Fu, Tao Zhuo, Hankun Jiang, Yin Lu, Hai Huang, Kewei Xu, Shengmeng Peng, Qing Yuan   +17 more
wiley   +1 more source

The Integrating the SETS (Science, Environment, Technology, Society) Framework into E-Worksheets for Natural Resource Education

Future Space
In the 21st century, students must have thinking skills and active learning to realize quality education. While this requires effective learning resources, existing traditional worksheets are often limited to memorization, failing to support the ...
Rafida Ramania Sahri, Purwanto, Supriono, Chanifah, Solikhin   +4 more
doaj   +1 more source

Harvester

, 1938
Yearbook for Pampa Senior High School in Pampa, Texas includes photographs of and information about the school, student body, teachers, and ...
Shryock, Betty, Pampa Senior High School
core  

An Expertise Transfer Framework For Autonomous Surgical Assistance

Advanced Science, EarlyView.
This study introduces an expertise transfer framework for procedure‐spanning autonomous surgical assistance. By emulating expert logic through hierarchical perception, attention modeling, and knowledge graph‐based decision‐making, the system provides near‐expert surgical view assistance.
Yuan Gao, Guangdi Chu, Wei Jiao, Yuchuan Zhong, Hang Yuan, Chengjun Li, Jinhua Li, Shuxin Wang, Bo Guan, Jianchang Zhao, Lizhi Pan, Haitao Niu, Jianmin Li   +12 more
wiley   +1 more source

The Impact of the Collaborative Creativity Learning Supported Google Earth on Students Spatial Thinking Ability

Future Space
Collaborative Creativity Learning (CCL) is a learning model that has the advantage of being applied, namely that students can find new ideas by designing, building and experiencing the surrounding environment and students can be directly involved in ...
Visna Shalsa Pratiwi, Purwanto, Akvian Erie Prawira, Nikmatur Rosidah, Arif Dio Esa Prayitno   +4 more
doaj   +1 more source

BUILDING CHARACTER OF ALTRUISM PRAXIS IN ENGLISH CLUB AT MAN KARAWANG

Getsempena English Education Journal, 2018
This study aimed at investigating the altruism praxis in English club extracurricular program at Senior High School. This study employed a case study and conducted in MAN Karawang.
Fina Aufar Laela Ibrahim
doaj   +1 more source

THE ANALYSIS OF THE TEACHER-MADE TEST FOR SENIOR HIGH SCHOOL AT STATE SENIOR HIGH SCHOOL 1 KUTACANE, ACEH TENGGARA

Jurnal Ilmiah Didaktika: Media Ilmiah Pendidikan dan Pengajaran, 2020
This study was designed to find out whether or not the English test made by the teacher called a teacher-made test was  valid  at state senior high school (SMAN) 1 Kutacane. The research design of this study was a qualitative descriptive research.
Lukmanul Hakim, Irhamsyah Irhamsyah
doaj   +1 more source

Metabolic Signatures for Liver Cancer Diagnosis and Mechanistic Insights: A Large‐Scale, Multicenter Study

Advanced Science, EarlyView.
A large‐scale multicenter serum metabolomics study (13 centers, n = 2,149) identified a 9‐metabolite + AFP diagnostic signature for liver cancer (AUC = 0.93). Among the signature, nicotinamide (NAM) was validated as an oncometabolite: NAM enhances NAD+ synthesis, activating SIRT1 to deacetylate and stabilize HIF1α, thereby driving glycolysis, MAPK ...
Yongjie Xu, Jiachen Wang, Chunmeng Ding, Changfa Xia, Yunyong Liu, Yuanjie Zheng, Sheng Chang, Shaokai Zhang, Yutong He, Ruifang Sun, Yunfeng Xi, Yan Liu, Kun Qian, Wanqing Chen   +13 more
wiley   +1 more source

Foundation Model‐Enabled Pathology‐Informed MRI Model for Preoperative Prediction of Vessels Encapsulating Tumor Clusters in Resectable Hepatocellular Carcinoma: A Multicenter Retrospective Study

Advanced Science, EarlyView.
PIVOT uses pathology‐derived morphologic and vascular representations from postoperative H&E and CD34 whole‐slide images to guide model development, while clinical inference requires only preoperative multiparametric MRI. Across five centers, PIVOT enabled accurate preoperative assessment of vessels encapsulating tumor clusters, stratified patients by ...
Zhehan Shen, Wanmin Liu, Xiaoming Li, Wenjie Zou, Yiman Li, Jie Yuan, Yasen Yimit, Shihang Wang, Linhao Qu, Hui Dong, Wei Chen, Ningyang Jia, Peijun Wang   +12 more
wiley   +1 more source

GENDER DIFFERENCE IN MATHEMATICS PERFORMANCE AMONGST SENIOR HIGH SCHOOL STUDENTS IN THE UPPER WEST REGION (UWR), GHANA

Kalamatika
Gender differences in mathematics performance have long concerned parents and policymakers in Ghana, especially in the UWR. This study examined these differences among high school students using an explanatory sequential mixed-methods design. Stratified
Mohammed Yikehere Marifa, Johnson Michael Nabie, Joshua Kai Dossey   +2 more
doaj   +1 more source