Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji +13 more
wiley +1 more source
Complications after complex device implantation: how important is implanter seniority? [PDF]
Scott PA +9 more
europepmc +1 more source
High electrical performance alone does not guarantee efficient bioelectronic signal transduction. Despite excellent mixed ionic‐electronic conduction, recordings from cardiomyocytes reveal that p(g2T‐TT)‐based OECTs predominantly transduce field potential FP‐like signals due to weak cell‐polymer coupling.
Giulia Zoe Zemignani +10 more
wiley +1 more source
Real Robotic Surgery: A New Paradigm of Surgical Approach. [PDF]
Pascotto B, Azagra JS.
europepmc +1 more source
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi +3 more
wiley +1 more source
Bridging knowledge gaps for healthy China 2030 plan: a province-wide assessment of primary healthcare workers' competencies and training preferences in Henan, China. [PDF]
Tarimo CS, Feng Y, Li Q, Bi Y, Song Y.
europepmc +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Climate change and sustainable healthcare practices in nursing: A multi-country exploratory online survey. [PDF]
Akore Yeboah E +4 more
europepmc +1 more source
Postsynaptic Complexin Mediates Constitutive Exocytosis of Nicotinic Acetylcholine Receptor
Beyond its established presynaptic role, complexin is identified as a postsynaptic regulator of neurotransmitter receptor trafficking. By promoting constitutive and activity‐dependent exocytosis of nicotinic acetylcholine receptors, complexin controls spontaneous synaptic signaling at the C.
Ya Wang +4 more
wiley +1 more source
Association between occupational health literacy and occupational stress among workers in metal mining, metallurgy and non-metallic manufacturing in Gansu, China. [PDF]
Zhang H, Zhao W, He Y, Wu J.
europepmc +1 more source

