Results 71 to 80 of about 321,342 (308)

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

Exogenous expression of ATP8, a mitochondrial encoded protein, from the nucleus in vivo

Molecular Therapy: Methods & Clinical Development
Replicative errors, inefficient repair, and proximity to sites of reactive oxygen species production make mitochondrial DNA (mtDNA) susceptible to damage with time.
David V. Begelman, Bhavna Dixit, Carly Truong, Christina D. King, Mark A. Watson, Birgit Schilling, Martin D. Brand, Amutha Boominathan   +7 more
doaj   +1 more source

Sen’s theorem for hierarchies

European Journal of Combinatorics, 2008
The conflict between the Pareto condition and individual rights within the area of social choice is analyzed for consensus functions on hierarchies.
openaire   +3 more sources

New High‐Tc Charge‐Transfer Multiferroicity in the Quasi‐2D Antiferromagnet CrSbS3

Advanced Science, EarlyView.
ABSTRACT Low‐dimensional magnets, particularly 2D systems, offer a rich platform for realizing unconventional multiferroic mechanisms, especially when multiple polarization channels coexist. In the quasi‐2D antiferromagnet CrSbS3, which crystallizes in the centrosymmetric orthorhombic space group Pnma and orders magnetically at TN ≈ 90 K, two ...
Hung‐Cheng Wu, Yu‐Hsin Liao, Chih‐Chung Tsai, Pei‐Ying Yang, Yu‐Hao Chang, Yu‐Hui Liang, D. Chandrasekhar Kakarla, Ajay Tiwari, C. Dhanasekhar, Chin‐Wei Wang, Daisuke Okuyama, Chia‐Nung Kuo, Chin‐Shan Lue, Tzu‐Hsuan Weng, Kung‐Hsuan Lin, Jau‐Wern Chiou, Chi‐Hung Lee, Hung‐Duen Yang   +17 more
wiley   +1 more source

Training load and intensity in triathlon: objective differences between sex, age, race distance preference and training phase across a cohort of 95 age-group triathletes over six months

Frontiers in Sports and Active Living
AimThis retrospective cohort study aimed to describe a large dataset of objective training load (TL) data from training sessions of age-group triathletes and to compare sex, age group, race distance preferences, and training phases.MethodsAn online ...
Leighton A. Wells, Samantha M. Hoffmann, Lyndell Bruce, Peter Kremer, Dan B. Dwyer   +4 more
doaj   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

La Semaine religieuse du diocèse de Sens et Auxerre : revue paraissant tous les samedis

, 1882
15 juillet 18821882/07/15 (A19,N28).Appartient à l’ensemble documentaire ...
Église catholique. Diocèse (Sens, Yonne). Auteur du texte
core  

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Rooted in culture, constrained by means: exploring crops and associated motivations among Masikoro and Antandroy farmers in Southwestern Madagascar

Journal of Ethnobiology and Ethnomedicine
Background Cultural groups play a key role in shaping and maintaining cultivated diversity, yet their influence is rarely considered in conservation or agricultural development initiatives.
E. Menguy, V. Labeyrie, A. S. Eladine, V. Rafidison, R. J. Randriamalala, D. Renard, S. M. Carrière   +6 more
doaj   +1 more source

Ferroelectric Devices for In‐Memory and In‐Sensor Computing

Advanced Science, EarlyView.
Inspired by biological systems, in‐memory and in‐sensor computing overcome von Neumann bottlenecks. Ferroelectric devices can mimic synaptic functions and sense stimuli like light or force, therefore are ideal for these paradigms. This review introduces the ferroelectric devices applied for in‐memory and in‐sensor computing, covering their structures ...
Hong Fang, Ronghuan Xie, Qiang Cao, Shishen Yan, Xiaolin Wang, Limei Zheng   +5 more
wiley   +1 more source