Results 111 to 120 of about 466,447 (335)

Role of the CXCR4/ALK5/Smad3 Signaling Pathway in Cancer-Induced Bone Pain

open access: yesJournal of Pain Research, 2020
Chong Peng,1,* Xue-Tai Chen,1,* Heng Xu,2 Li-Ping Chen,2 Wen Shen1,2 1Jiangsu Province Key Laboratory of Anesthesiology and Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application Technology, Xuzhou Medical University, Xuzhou, Jiangsu ...
Peng C, Chen XT, Xu H, Chen LP, Shen W
doaj  

Clickbait? Sensational Headline Generation with Auto-tuned Reinforcement Learning [PDF]

open access: yesarXiv, 2019
Sensational headlines are headlines that capture people's attention and generate reader interest. Conventional abstractive headline generation methods, unlike human writers, do not optimize for maximal reader attention. In this paper, we propose a model that generates sensational headlines without labeled data. We first train a sensationalism scorer by
arxiv  

Sensation and loss [PDF]

open access: yesNature, 2013
An injury to the spine — the long bony assemblage that supports the upper body and the spinal cord that carries nerve signals — can be grim and costly. By Bill Cannon.
openaire   +3 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Neurotrophic keratitis after micropulse transscleral diode laser cyclophotocoagulation. [PDF]

open access: yes, 2019
PurposeTo report two cases of neurotrophic keratitis (NK) after micropulse transscleral cyclophotocoagulation (MP-TCP).ObservationsTwo patients with predisposing factors for decreased corneal sensation developed NK 1 month after MP-TCP. Both patients did
Han, Ying   +4 more
core   +1 more source

Sensations of the skin. [PDF]

open access: yesPsychological Review, 1894
n ...
openaire   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

The Effects of Men\u27s Lacrosse Protective Equipment on Thermoregulation and Perceptions During Exercise Heat Stress [PDF]

open access: yes, 2019
The effects of men\u27s lacrosse protective equipment on thermoregulation and perceptions during exercise heat stress Amanda P. Glasgow: Exercise Science Research Center, University of Arkansas, Fayetteville, AR.
Glasgow, Amanda
core   +3 more sources

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

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