Results 131 to 140 of about 246,654 (347)
Willingness to experience unpleasant thoughts, emotions, and bodily sensations at admission does not predict treatment outcome in inpatients with obsessive–compulsive disorder [PDF]
, 2023 Eva M. Zisler +3 more
openalex +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Impulse control disorders in an inpatient psychiatry unit of a university hospital
Psychiatry and Clinical Psychopharmacology, 2021 Objective: Like other comorbid disorders, comorbidity of impulse control disorders (ICDs) in various psychiatric disorders may complicate the diagnostic work-up of patients which might further influence the outcome and the treatment.
Lut Tamam +3 more
doaj
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Depression’s Connection to Self-Harming Behavior in Adolescents [PDF]
, 2016 Self-harming behavior amongst adolescents has increased in prevalence throughout America. There is a direct connection between depression and self-harming behaviors in adolescent students.
Hendrick, Michael T.
core +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
BMC PsychologySound perception extends beyond the boundaries of auditory sensation, encompassing an engagement with the human body. In this study, we examined the relationship between our perception of sound pitch and our bodily sensations, while also exploring the ...
Tatsuya Daikoku +2 more
doaj +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Pengaruh Sensation Seeking terhadap Internet Gaming Disorder pada Gamers Usia 16-24 Tahun
, 2023 Farhan Fauzan, Lilim Halimah
openalex +2 more sources