Results 41 to 50 of about 204,950 (284)
Background and objective: The purpose of this research is to study the relation between emotional intelligence, sensation seeking and marital satisfaction among female teachers in the city of Borujerd.Materials and Methods: The statistical population is ...
Hatam Siavoshi +3 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Many personality traits are popular sources of research for a short time, and then, like the constructs on which they are based, they gradually fade away. In contrast, Sensation Seeking (otherwise known as Novelty Seeking, Arousal Seeking, Excitement Seeking, and other “seeking” labels) has had a steady increase in citations over the half century since
Joseph Glicksohn, Marvin Zuckerman
openaire +2 more sources
Consumer innovative behavior in vacation travel [PDF]
This paper focuses on the study of innovative behavior of tourists through the dimensions of sensation seeking. To our knowledge, few studies have explored the dimensions of sensation seeking in relation to the innovative behavior of tourists in their ...
López-Bonilla, Jesús Manuel +2 more
core
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Sensation seeking and impulsivity as predictors of aggression in adolescents [PDF]
Adolescence is a stage in which impulsivity and sensation seeking are presented as two factors that come together with a wide range of changes inherent to adolescent development.
José J. GÁZQUEZ +3 more
doaj
Online and live regular poker players: Do they differ in impulsive sensation seeking and gambling practice? [PDF]
Background and aims Online gambling appears to have special features, such as anonymity, speed of play and permanent availability, which may contribute to the facilitation and increase in gambling practice, potentially leading to problem gambling.
Barrault, Servane, Varescon, Isabelle
core +5 more sources
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source

