Results 41 to 50 of about 206,470 (305)

Sensation seeking among high- and low-risk sports participants : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]

, 1996
The purpose of the present study was to investigate the sensation seeking tendencies of select New Zealand athletes. A "sensation seeker" is thought to be a person who needs varied, complex, novel, and intense forms of stimulation and experience and who ...
Jack, Sarah Jane
core  

Perceived parental permissiveness toward gambling and risky behaviors in adolescents [PDF]

, 2014
Background and aims Perceived parental permissiveness toward gambling may relate to adolescents’ engagement in various risky behaviors. To examine this possibility, we analyzed data from a high-school based risk-behavior survey to assess relationships ...
Hoff, Rani A., Krishnan-Sarin, Suchitra, Leeman, Robert F., Patock-Peckham, Julie A., Potenza, Marc N., Rugle, Loreen J., Steinberg, Marvin A.   +6 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Sensation seeking, non-contextual decision making, and driving abilities as measured through a moped simulator. [PDF]

, 2017
The general aim of the present study was to explore the relations between driving style (assessed through a moped riding simulator) and psychological variables such as sensation seeking and decision making. Because the influences of sensation seeking and
Gianfranchi, Evelyn, Spoto, Andrea, Tagliabue, Mariaelena, Vidotto, Giulio   +3 more
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Electrocortical correlates of hypersensitivity to large immediate rewards in sensation seeking

NeuroImage, 2023
Sensation seeking and delay discounting are strong predictors of various risk-taking behaviors. However, the relationship between sensation seeking and delay discounting remains elusive.
Ya Zheng, Chenlu Guan, Zhao Wang, Wendeng Yang, Bo Gao   +4 more
doaj   +1 more source

Self-affirmation improves music performance among performers high on the impulsivity dimension of sensation seeking [PDF]

, 2018
In the light of evidence that self-affirmation can mitigate the negative effects of stress on outcomes, this study tested whether a self-affirmation manipulation could improve undergraduate students’ achievement in a formal musical performance ...
Amico K. R., Cohen G. L., Creswell J. D., Cyders M. A., Dickman S. J., Donna C. Jessop, Düring C., Elliot A. J., Epton T., Ericsson K. A., Evenden J. L., Eysenck M. W., Eysenck S. B., Hambrick D. Z., Harris P. R., Kenny D., Knezevic-Budisin B., Laura Ritchie, Lozano J. H., McPherson G. E., Miksza P., Nieuwenhuys A., Patton J. H., Peter R. Harris, Schmeichel B. J., Sharma L., Sherman D. K., Sherman D. K., Sherman D. K., Sloboda J. A., Sobell L. C., Sophie Goodwin, Spinella M., Steele C. M., Susan Churchill, Welch G., Whiteside S. P., Zuckerman M.   +37 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Consumer innovative behavior in vacation travel [PDF]

, 2011
This paper focuses on the study of innovative behavior of tourists through the dimensions of sensation seeking. To our knowledge, few studies have explored the dimensions of sensation seeking in relation to the innovative behavior of tourists in their ...
López-Bonilla, Jesús Manuel, López-Bonilla, Luis Miguel, Sanz Altamira, Borja   +2 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source