Results 71 to 80 of about 6,140,004 (297)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

fablabbcn/smartcitizen-onboarding-app: Making Sense Project Final Release

open access: yes, 2018
<p>The Making Sense on boarding for Smart Citizen</p ...
Lucas Lorenzo, Guillem Camprodon
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Moral Hermeneutics and Technology: Making Moral Sense through Human-Technology-World Relations

open access: yes, 2023
In Moral Hermeneutics and Technology: Making Moral Sense through Human-Technology-World Relations, Olya Kudina explores the role of technology in the way people arrive at their moral intuitions and choices and revise their moral commitments, a phenomenon
Kudina, O. (author)
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

It Seems So Simple Now: Complementary and Alternative Medicine as a Resource for Sense-Making

open access: yes, 2009
BRENTON, JOSLYN. "It All Seems So Simple Now" : The Use of Complementary and Alternative Medicine for Sense-Making. (Under the direction of Michael Schwalbe).
Brenton, Joslyn Jane
core  

Making sense of big datA

open access: yesBioTechniques, 2016
As data sets grow in size, new computational tools are needed. Jeffrey Perkel looks at the ins and outs of data analysis.
Jeffrey Perkel
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Making Sense Beauty, Creativity, and Healing

open access: yes, 2014
Regardless of field, from the art world to healthcare delivery, there is a growing need for practically useful theory and theoretically informed practice.
Lee, Bandy   +2 more
core  

Making Sense of Denial in Sexual Offenders

open access: yes, 2014
Denial in sexual offenders represents the first barrier to successful treatment a clinician is likely to face. Most sex offender treatment programs devote significant time to overcoming denial, with most programs having a focus on disclosure and ...
Thorne, K.   +7 more
core   +1 more source

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