Results 141 to 150 of about 1,797,253 (294)

Reduced Sense of Agency in Human-Robot interaction

open access: yes, 2018
In the presence of others, sense of agency (SoA), i.e. the perceived relation-ship between our own actions and external events, is reduced. This effect is thought to contribute to diffusion of responsibility. The present study aimed at examining humans’ SoA when interacting with an artificial embodied agent.
Wykowska, Agnieszka   +4 more
openaire   +4 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

The Perceptual Sense of Agency

open access: yesReview of Philosophy and Psychology
Abstract The sense of agency is the experience of predicting, initiating, or controlling actions. In this paper, I provide a novel account of the sense of agency that appears in perceptual consciousness. I follow theorists such as Bayne and Prinz in suggesting that the
openaire   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Dynamics of Faculty Engagement in the Movement for Democracy's Education at Nothern Arizona University: Backgrounds, Practices, and Future Horizons [PDF]

open access: yes, 2015
As scholarship has become increasingly narrow and disconnected from public life, Kettering research has documented an intense sense of malaise in higher education, what Harry Boyte has called a loss of civic agency.
Blase Scarnati, Romand Coles
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

The Phenomenology of Joint Action: Self-Agency vs. Joint-Agency [PDF]

open access: yes, 2012
This chapter aims at investigating the phenomenology of joint action and at gaining a better understanding of (1) how the sense of agency one experiences when engaged in a joint action differs from the sense of agency one has for individual actions and ...
Pacherie, Elisabeth
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

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