Results 31 to 40 of about 53,927 (215)

Sense of coherence among patients with rheumatoid arthritis

Pielęgniarstwo XXI Wieku, 2017
SENSE OF COHERENCE AMONG PATIENTS WITH RHEUMATOID ARTHRITIS Introduction. Sense of coherence (SOC-29) clarifies the relationship with health. High SOC in patients with rheumatoid arthritis puts faith in the meaning of life. Makes you want to be healthy
Mariola Ejdys, Olga Bielan
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Latent profile analysis of sense of coherence and relationship with meaning of life and professional identity among nursing undergraduate

BMC Nursing
Background Enhancing nursing undergraduates’ sense of coherence is crucial for the growth of the nursing workforce. Yet, existing research primarily examines the aggregate level of sense of coherence among nursing undergraduates and its correlations with
Yating Liu, Dudu Zhang, Song Ge, Shanshan Wang, Xin Li, Zhenxiang Zhang, Beilei Lin, Suyan Chen, Yongxia Mei   +8 more
doaj   +1 more source

Factors influencing career choice in anaesthesiology

Indian Journal of Anaesthesia, 2012
Background: There is a shortage of anaesthesiologists in India. The factors that prompt medical students to opt for anaesthesiology as their career are not known; neither do we have any mechanism to know a student′s stress-bearing ability before he/she ...
Asha Tyagi, Surendra Kumar, Ashok Kumar Sethi, Upreet Dhaliwal   +3 more
doaj   +1 more source

The relationship of dental students’ characteristics to social support, psychosocial factors, lifestyle, and quality of life

Health Psychology and Behavioral Medicine, 2022
Objective To examine the relationships between sociodemographic characteristics, student academic information, social support, sense of coherence, anxiety, lifestyle, and quality of life among dental students.Methods: A cross-sectional study among 233 ...
Andréa Neiva da Silva, Deison Alencar Lucietto, Maria Victória da Silva Bastos, Thainá Queiroz do Nascimento, Mario Vianna Vettore   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Relationship between sense of coherence and professional identity in nursing students: the chain mediating effect of academic emotion and self-esteem

BMC Nursing
Background The psychological conditions of nursing students are quite important, and professional identity is an important part of the stable development of the nursing profession.
Huan Liu, Jin Li, Xiujuan Feng, Rui Liang, Yanan Qi, Jing Zhang   +5 more
doaj   +1 more source

The sense of coherence and physical activity among secondary-school graduates living in the Lubelskie Province

Fides et Ratio, 2019
The issues which are the focus of the research problem addressed here are related to identifying a) the sense of coherence among secondary-school graduates, b) physical activity of secondary-school graduates, and c) mutual correlations between the two ...
Agnieszka Linca-Ćwikła
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source