Results 111 to 120 of about 18,556 (292)
Engraftment of sheep splenic lymphocytes into NBSGW mice and application in Brucella infection
Animal Models and Experimental Medicine, EarlyView.A sheep splenocyte‐reconstituted mouse model (Sh‐Spl mice) was established via intravenous injection of sheep splenic lymphocytes into immunodeficient mice to evaluate Brucella infection. Abstract Background The development of immune reconstituted xenograft mouse models has addressed the limitations imposed by interspecies immunological differences in ...
Xiaowei Wang +9 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.This study establishes an NPG (NOD.Cg‐Prkdcscid Il2rgtm1/Vst) mouse model for severe monkeypox virus infection in immunocompromised hosts, demonstrating dose‐dependent disease severity and revealing that unbalanced pro‐inflammatory cytokine release drives pathogenesis, providing insights for therapeutic interventions. Abstract The global spread of mpox
Na Li +11 more
wiley +1 more source
How humorous is AI? Exploring ChatGPT's role in humor generation and human-AI interaction
Computers in Human Behavior ReportsThe rapid evolution of artificial intelligence has raised important questions about its ability to replicate nuanced human cognitive functions -- particularly humor generation.
Yi Cao, Jiahao Cao, Yubo Hou, Li-Jun Ji
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley +1 more source
Annals of Neurology, EarlyView.Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello +20 more
wiley +1 more source
Passages of the Humor of Humors
Miscelánea Comillas, 2019 Ten passages of humor compose an unfinished mosaic of semblances that follow one another: from the singular to the plural; humors and colors; humor with laughter, without laughter and with a smile; good mood and bad mood; humor and philosophy or the ...
Luis Bueno Ochoa
doaj
Annals of Neurology, EarlyView.Objective Epstein–Barr virus (EBV) has been implicated in the pathogenesis of multiple sclerosis (MS). Elevated immunoglobulin G (IgG) titers against EBV nuclear antigen 1 (EBNA1) represent the most consistent serological marker of MS risk, with levels remaining persistently elevated following disease onset.
Malina Behrens +9 more
wiley +1 more source
Does Sense of the Humor Make Sense in the Classroom?
Revista Electrónica Educare, 2011 This paper studies the importance of humor as a teaching strategy in the classroom, considering the usual lack of motivation and boredom. To analyze whether the “happy teaching and happy learning” may increase effectiveness in the teaching-learning ...
Freddy Antonio González-Ynfante
doaj
The Anatomical Record, EarlyView.Abstract The middle Permian represents a critical interval in therapsid evolution, when gorgonopsians emerged as some of the first specialized apex predators within terrestrial ecosystems. Despite their significance, the early diversification of Gorgonopsia in Gondwana remains poorly understood due to scarcity and fragmentary material.
Zanildo Macungo +5 more
wiley +1 more source