Results 51 to 60 of about 63,800 (252)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

FEATURES OF THE SENSE OF JUSTICE IN THE YOUTH OF DAGESTAN

Вестник Кемеровского государственного университета, 2015
Article retractedThe paper presents the features of formation of the sense of justice and legal culture in Dagestan youth. On the basis of sociological poll the author identified the role of the regional factors that have positive influence on the ...
N. A. Asvarov
doaj  

Parents Representations of the Legal Socialization of Children [PDF]

Психологическая наука и образование (2007. Online), 2014
Insufficient knowledge about the impact of parental education on the development strategies of justice of children and adolescents in destabilizing the social conditions of modern society determines the relevance of the author's work.
Kalashnikova A.S., , Shalunova A.D.,
doaj  

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

THE POSITION OF LAW IN THE HIERARCHY OF SOCIAL VALUES

Вестник Кемеровского государственного университета, 2013
The paper examines the issue of the relative value of the lawfor the development of the individual and of the society, basing of B. A. Kistyakovsky’sarticle «In defense of the law» in «Vekhi» a collection of articles on the Russian intelligentsia.
S. V. Zarutskaya
doaj  

The Integration of the Kalmyks into the Legal System of the Russian Empire in the Late 18th and the First Half of the 19th Centuries. Translation from Russian

Журнал Фронтирных Исследований
This article analyzes the specific features of the integration of the Kalmyk population into the legal system of the Russian Empire over the period from the late 18th to the first half of the 19th century. Following the abolition of Kalmyk statehood, the
Maria V. Chernik
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

“Perfect idiots”: senses of justice, moral insults and discursive exclusion from the perspective of three residents of a Rio de Janeiro favela

Anuário Antropológico
In this article, we explore the reactions and comments of three residents of a Rio de Janeiro favela in response to the publicity and repercussions of the circumstances surrounding the death of a resident of a neighbouring favela.
Marcus Cardoso, Carolina Barreto Lemos
doaj   +1 more source