Results 101 to 110 of about 952,790 (314)

Moving a rubber hand that feels like your own: dissociation of ownership and agency

Frontiers in Human Neuroscience, 2012
During voluntary hand movement, we sense that we generate the movement and that the hand is a part of our body. These feelings of control over bodily actions, or the sense of agency, and the ownership of body parts are two fundamental aspects of the way ...
Andreas eKalckert, H Henrik Ehrsson
doaj   +1 more source

Perceptions of the Maltese public towards local Marine Protected Areas [PDF]

, 2015
The marine environment represents a central component of Malta's local environment, and its ecosystem services play a vital role in supporting the economy as well as human well-being.
Mifsud, Mark C., Verret, Marielle
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Specifying and Verifying Concurrent Algorithms with Histories and Subjectivity [PDF]

, 2014
We present a lightweight approach to Hoare-style specifications for fine-grained concurrency, based on a notion of time-stamped histories that abstractly capture atomic changes in the program state.
A. Cerone, A. Gotsman, A. Gotsman, C.J. Bell, K. Svendsen, M. Fu, P. Rocha Pinto da, T. Dinsdale-Young, T. Elmas, V. Vafeiadis, X. Feng   +10 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

When the Body Feels Foreign: A Case of Body Ownership disturbance in Brief Psychotic Disorder

Kerala Journal of Psychiatry
Deficits in the sense of self are well-documented in psychotic disorders, but evidence regarding disturbances in body ownership remains inconclusive.
Sreya Mariyam Salim, Shabeer Chenganakkattil, Noufal KT, Jithu VP   +3 more
doaj   +1 more source

Corporate Social Responsibility in Large Family and Founder Firms [PDF]

Based on arguments about long-term orientation and corporate reputation, we argue that family and founder firms differ from other firms with regard to corporate social responsibility.
Block, J.H., Wagner, M.
core   +1 more source

»I can"t have your pains« First Person Statements and the Ambiguity of Meaning [PDF]

, 2002
In PI 246 Wittgenstein remarks: »In what sense are my sensations private?« This question is embedded in a broader context that deals with the possibility of a private language (cf. PI 243-315).
Munz, Volker A.
core