Results 41 to 50 of about 19,741 (312)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Development and Performance Study of VAV, Constant Temperature and Humidity Unit Housed in a Basement

open access: yesZhileng xuebao, 2018
According to the characteristics of high temperature and humidity in a basement, a variable air volume (VAV), constant temperature and humidity unit was manufactured and investigated experimentally. Two sets of experiments were carried out on a prototype,
Weng Wenbing, Li Shufeng, Wang Shaoqing
doaj  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Footprint issues in scintillometry over heterogeneous landscapes [PDF]

open access: yesHydrology and Earth System Sciences, 2009
Scintillometry is widely recognized as a potential tool for obtaining spatially aggregated sensible heat fluxes at regional scales. Although many investigations have been made over contrasting component surfaces, few aggregation schemes consider ...
A. Olioso, Z. Su, W. J. Timmermans
doaj  

Thermal equilibrium analysis and experiment of molten slag modification by use of its sensible heat

open access: yes工程科学学报, 2016
Preparing high added-value materials from molten slag directly by modifying molten slag has drawn a great interest in the utilization of molten slag because of its high efficiency during the integrated utilization of the heat and slag.
LU Xiang   +4 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Estimation of Sensible and Latent Heat Fluxes from Different Ecosystems Using the Daily-Scale Flux Variance Method

open access: yesAtmosphere
A daily-scale flux variance (FV) method, which employs low-frequency air temperature measurements, was assessed against eddy covariance (EC) measurements of sensible and latent heat fluxes at four sites representing grassland and cropland ecosystems. The
Yanhong Xie   +6 more
doaj   +1 more source

Particle flux–gradient relationships in the high Arctic: emission and deposition patterns across three surface types [PDF]

open access: yesAtmospheric Chemistry and Physics
The Arctic is experiencing a warming much faster than the global average and aerosol–cloud–sea–ice interactions are considered to be one of the key features of the Arctic climate system.
T. Mathes   +10 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Long-term daily dataset of surface sensible heat flux and latent heat release over the Tibetan Plateau based on routine meteorological observations

open access: yesBig Earth Data, 2022
As the main components of the atmospheric heat source/sink over the Tibetan Plateau (TP), up-to-date spatiotemporal fields of surface sensible heat flux and latent heat release by precipitation are vital for investigating the local land–atmosphere ...
Anmin Duan   +4 more
doaj   +1 more source

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