Results 61 to 70 of about 19,741 (312)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Micrometeorology and heat balance over the fast ice
Antarctic Record, 1997 Micrometeorological conditions were observed over fast ice with overlying thick snow cover and underlying deep sea approximately in the center of Ongul Strait in Lutzow-Holm Bay, Antarctica, from the end of March to the beginning of December in 1990.
Kiyotaka Nakagawa
doaj +1 more source
Downwelling longwave radiation and sensible heat flux observations are critical for surface temperature and emissivity estimation from flux tower data. [PDF]
Sci Rep, 2022 Thakur G +4 more
europepmc +1 more source
Energy Storage by Sensible Heat for Buildings [PDF]
, 2017 International ...
Fan, Yilin, Luo, Lingai
openaire +2 more sources
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Comparison of heat storage systems employing sensible and latent heat
International Journal of Energy Research, 1999 This study makes an evaluation of the performances of heat storage systems destined for power plants with a discontinuous power source such as nuclear fusion. Two classes of heat storage systems are investigated: heat storage systems based on first sensible heat storage and second latent heat storage.
G. Van Den Branden +2 more
openaire +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source