Results 111 to 120 of about 1,047,682 (240)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
AVANT. The Journal of the Philosophical-Interdisciplinary Vanguard, 2015 The book edited by Massimiliano Cappuccio and Tom Froese is aimed at understanding non-sense in cognition and the process of sense-making. The authors of twelve chapters included in the book focus on different aspects of sense-making in diversified aspects of cognition.
openaire +2 more sources
STUDY ON THE PRODUCTION COST PRICING MODEL OF QUANTITATIVE REMOTE SENSING PRODUCTS
, 2015 Since the forming of sustainable business models of remote-sensing products and services will be an inevitable development trend, it is necessary to design the specific and rational pricing model for quantitative remote sensing products (QRSPs). Based on
Jiao, Jian +7 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Thrinax radiata Seed Germplasm Dynamics Analysis Assisted by Chaos Theory
Mathematical and Computational ApplicationsThis study examines the contrast in the nonlinear dynamics of Thrinax radiata Lodd. ex Schult. & Schult. f. Seed germplasm explored by optical and electrical signals.
Hilario Martines-Arano +5 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
JPhys EnergyCarbon dots (CDs) are environmentally benign, strongly photoluminescent, metal free nanoparticles. Interfacing them with tailor-made organic semiconductors possesing an ordered channel structure such as covalent organic frameworks (COFs) promises to ...
Julian Feijoo +2 more
doaj +1 more source
Design and Optimization of a Hybrid Design for Quantum Transduction
SensorsThis study presents the mechanical design and analysis of a quantum electro-optical transducer engineered to operate at millikelvin temperatures within a dilution refrigerator.
Enrico Bargagna +7 more
doaj +1 more source