Results 81 to 90 of about 821,450 (338)

Elucidating the activation mechanism of the proton-sensing GPR68 receptor [PDF]

open access: gold, 2023
Christos Matsingos   +3 more
openalex   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Quantum dynamics of the avian compass

open access: yes, 2014
The ability of migratory birds to orient relative to the Earth's magnetic field is believed to involve a coherent superposition of two spin states of a radical electron pair. However, the mechanism by which this coherence can be maintained in the face of
C. D. Treiber   +7 more
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Optimization of TiO2 and PMAPTAC Concentrations of a Chemical Humidity Sensing Mechanism

open access: yesSensors, 2009
This work aims to achieve an optimization of the TiO2 and PMAPTAC concentrations in a chemical resistive-type humidity sensing mechanism (RHSM). Our idea is based primarily on the modeling of the sensing mechanism.
Samir Barra   +4 more
doaj   +1 more source

Screening of Indonesia Medicinal Plants Producing Quorum Sensing Inhibitor [PDF]

open access: yes, 2011
Antibiotic resistance of bacteria lead to create different way in the pathogen bacteria handling such us inhibit their quorum sensing mechanism. The goal of this study is to search quorum sensing inhibitor of seven Indonesia medicinal plants.
Artadana, Ida Bagus Made   +7 more
core  

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Recoverable Detection of Dichloromethane by MEMS Gas Sensor Based on Mo and Ni Co-Doped SnO2 Nanostructure

open access: yesSensors
The challenging problem of chlorine “poisoning” SnO2 for poorly recoverable detection of dichloromethane has been solved in this work. The materials synthesized by Ni or/and Mo doping SnO2 were spread onto the micro-hotplates (
Mengxue Xu   +10 more
doaj   +1 more source

Role of spatial averaging in multicellular gradient sensing

open access: yes, 2015
Gradient sensing underlies important biological processes including morphogenesis, polarization, and cell migration. The precision of gradient sensing increases with the length of a detector (a cell or group of cells) in the gradient direction, since a ...
Fancher, Sean   +4 more
core   +1 more source

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