Results 31 to 40 of about 273,001 (210)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

THE DEVELOPMENT AND INDUSTRIALIZATION RECOMMENDATION OF CURRENT AERIAL REMOTE SENSING TECHNOLOGY [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2013
At present, the research development and industrialization of aerial remote sensing technology in China are faced with enormous requirements and developing chance. It is the strategic selection for remote sensing technology to perfect the construction of
Z. Hong
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Development and Application of Fiber-Optic Sensing Technology for Monitoring Soil Moisture Field

Frontiers in Sensors, 2022
Accurate acquisition of the moisture field distribution in in situ soil is of great significance to prevent geological disasters and protect the soil ecological environment.
Meng-Ya Sun, Bin Shi, Jun-Yi Guo, Hong-Hu Zhu, Hong-Tao Jiang, Jie Liu, Guang-Qing Wei, Xing Zheng   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Revolutionizing Process Automation: The Synergy of Low-Code Development Platforms, Robotic Process Automation, and Integrated Smart System Platform

IEEE Access
The paper proposes a novel architecture that combines Robotic Process Automation (RPA), Low-Code Development Platforms (LCDP), and the Integrated Smart System Platform (ISSP) to enhance urban automation.
Noor Falih, Suhono Harso Supangkat, Fetty Fitriyanti Lubis, Okyza Maherdy Prabowo   +3 more
doaj   +1 more source

Promoting Contemplative Culture through Media Arts

Multimodal Technologies and Interaction, 2019
This paper presents the practice of designing mediation technologies as artistic tools to expand the creative repertoire to promote contemplative cultural practice.
Jiayue Wu
doaj   +1 more source