Results 181 to 190 of about 3,039,015 (218)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Climate change as a modifier of paediatric lung-function trajectories. [PDF]

Eur Respir Rev
Drummond D, Renz HE, Beri C, Rosa MJ, Hart JE, Murphy MP, McElvaney NG.   +6 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Beyond the Textbook: An HBM and SCT Analysis of Adolescent Reproductive Health Education in Rural Bangladesh. [PDF]

Public Health Chall
Billah M, Uddin MF.
europepmc   +1 more source

Feasibility of Using Digital Clinical Records to Identify Factors Associated with Nursing-Sensitive Outcomes During Hospitalization: A Pilot Study. [PDF]

Nurs Rep
Finiguerra I, Gianino MM, Vacchelli R, Demasi M, Pappalardo L, Albanese C, Binello E, Borghin G, Cappello S, Cavagnini N, Durante S, Ferraris A, Gorgonzola F, Munaro B, Pellegrino S, Russo C, Tedino L, Minniti D, Di Gioia S.   +18 more
europepmc   +1 more source

LRRC32 Mediates Resistance to Everolimus in Hormone Receptor-Positive, HER2-Negative Breast Cancer. [PDF]

Cancer Manag Res
Wang L, Chen X, Li X, Wang Y, Shen R.
europepmc   +1 more source

A Novel Variable-Pulse Monopolar RF Mode Selectively Targets the Upper Dermis to Improve Barrier Dysfunction in Sensitive Skin. [PDF]

Ann Dermatol
Ryu HG, Kong Y, Kim S, Kim SY, Choi YJ, Kim W, Kim WS.   +6 more
europepmc   +1 more source

Bringing Shame Out of the Shadows. [PDF]

Int J Ment Health Nurs
Isobel S.
europepmc   +1 more source

Development of a clinical speech corpus with temporally aligned sensitive health information annotations. [PDF]

BMJ Health Care Inform
Hsu HC, Fang LC, Mir TH, Chen CT, Feng HH, Lai JR, Nandy P, Panchal O, Liao WH, Tien YZ, Chen PZ, Lin YR, Dai HJ, Jonnagaddala J.   +13 more
europepmc   +1 more source