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obophenotype/bio-attribute-ontology: 2022-05-11 Release

, 2022
What's Changed Add hp import, fix onset pattern by @matentzn in https://github.com/obophenotype/bio-attribute-ontology/pull/94 Fix logical definition for 'body fluid levels'. by @balhoff in https://github.com/obophenotype/bio-attribute-ontology/pull/67
Chris Mungall, uberon, Meghan Balk, Jim Balhoff, Nicole Vasilevsky, Nico Matentzoglu, Dan Keith, Melissa Haendel, Ray Stefancsik, kallia-p, Charles Tapley Hoyt, paolaroncaglia, diatomsRcool   +12 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Non-Equi join operation algorithm for multi-attribute [PDF]

Jisuanji gongcheng, 2019
To reduce the computational cost of multi-attribute non-equi join operation,an non-equi join operation algorithm MIEJoin based on attribute optimization is proposed.The tuples are sorted by join attribute,the candidate set size of each join attribute
MENG Qingqiang,HE Haoqi,BI Nifei,ZHAO Bin,JI Genlin
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Fair Classification Without Sensitive Attribute Labels via Dynamic Reweighting

Applied Sciences
Fairness-aware classification with respect to sensitive attributes, such as gender and race, is one of the most important topics in machine learning. Although numerous studies have made outstanding progress through various approaches, one key limitation ...
Pilhyeon Lee, Sungho Park
doaj   +1 more source

Extended K-Anonymity Models Against Attribute Disclosure

, 2009
P-sensitive K-anonymity model has been recently defined as a sophistication of K-anonymity. This new property requires that there be at least P distinct values for each sensitive attribute within the records sharing a combination of key attributes ...
Xiaoxun Sun, Hua Wang, Sun, Xiaoxun, Sun, L, Sun, Lili, Lili Sun, Sun, X, Wang, Hua   +7 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

A Conditional Diffusion Graph Privacy Protection Model Based on Task-Aware Attention and Hierarchical Adversarial Constraints

Mathematics
Graph representation learning models inherently capture structural and attribute correlations, which may lead to significant privacy risks under attribute inference attacks.
Yifan Wang, Jinchuan Tang, Shuping Dang
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

User Access Control Scheme for Electrified Wire Netting on Mobile APP [PDF]

Jisuanji gongcheng, 2018
For sensitive data protection and user security access issues in electric power enterprise,this paper proposes an access control scheme for user of electrified wire netting.When the user wants to query the data,he must interact with the network server in
LI Ming,FANG Yuan,LIU Jun,YU Junhao
doaj   +1 more source