Results 211 to 220 of about 4,715,263 (253)

The Role of Dominant Lesion Site and SUVmax in the Depth of PSA Response in Metastatic Hormone-Sensitive Prostate Cancer. [PDF]

Biomedicines
Akgüner G, Güleşen Aİ, Yıldırım ÖA.   +2 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Measures matter: assessing childhood maltreatment and emotion dysregulation in a transdiagnostic sample. [PDF]

Eur J Psychotraumatol
Seitz KI, Schalinski I, Renneberg B, Heinrichs N, Brühl A, Steinmann S, Neukel C, Herpertz SC.   +7 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Historical Changes and Drivers of Aerosol Acidity in Switzerland under Emission Reduction and Its Implication of Regulation Policies. [PDF]

Environ Sci Technol
Zhang J, Waseem A, Baccarini A, Kakavas S, Hüglin C, Nenes A.   +5 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Beyond Binary ICU Admission: Duration-Sensitive Evaluation and Patient-Level Reclassification of Textbook Outcome After Colorectal Cancer Surgery. [PDF]

J Clin Med
Ozcan A, Gunes G, Bal A, Unsal A.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Conflict-Related Disruption of Oncology Drug Supply in the Gulf and Measures to Maintain Cancer Care Continuity. [PDF]

Glob J Qual Saf Healthc
Abusanad A, Esba LCA, Kullab S.
europepmc   +1 more source