Results 81 to 90 of about 17,148,641 (166)

A Mathematical Model for the Within-Host Dynamics of Malaria Parasite with Adaptive Immune Responses

open access: yesInternational Journal of Mathematics and Mathematical Sciences
Mathematical analysis of epidemics is crucial for long-term disease prediction and helps to guide decision-makers in terms of public health policy. In this study, we develop a within-host mathematical model of the malaria parasite dynamics with the ...
Jemal Muhammed Ahmed   +2 more
doaj   +1 more source

A diffusion-based HIV model with inflammatory cytokines and adaptive immune impairment

open access: yesFrontiers in Applied Mathematics and Statistics
HIV continues to pose a critical threat to global public health, contributing to a high number of deaths worldwide. The virus predominantly attacks CD4+T lymphocytes, which are essential for coordinating immune responses.
N. H. AlShamrani
doaj   +1 more source

Global stability analysis of a fuzzy HIV–TB co-infection model with environmental TB transmission

open access: yesScientific African
Human Immunodeficiency Virus (HIV) and Tuberculosis (TB) co-infection remains a significant global health challenge, further complicated by environmental transmission and inherent biological uncertainties.
Dickson D. Luambano   +2 more
doaj   +1 more source

A Nonlinear Quantum-Deformation-Fractional Model for Memory-Dependent Glucose–Insulin–Glucagon Dynamics With Real-Data Validation

open access: yesJournal of Applied Mathematics
This study develops a nonlinear (q,τ)-fractional biophysical model for memory-dependent glucose–insulin–glucagon regulation. The model is motivated by the fact that metabolic regulation is governed by delayed insulin action, counter-regulatory glucagon ...
Rabha W. Ibrahim   +2 more
doaj   +1 more source

Stochastic analysis of Mpox epidemiology with vaccination strategies and environmental persistence

open access: yesScientific Reports
In the context of global preparedness and response strategies for Mpox outbreaks, we develop a comprehensive mathematical model to investigate its transmission dynamics, integrating critical factors such as vaccination coverage and environmental ...
Faizunnesa Khondaker, Md. Kamrujjaman
doaj   +1 more source

Stability and bifurcation analysis of a nested multi-scale model for COVID-19 viral infection

open access: yesComputational and Mathematical Biophysics
In this study, a nested multi-scale mathematical model is proposed and studied for COVID-19 viral infection. The well-posedness of the multi-scale model is discussed, followed by the stability analysis of the equilibrium points. The proposed model admits
Chhetri Bishal, Vamsi Dasu Krishna Kiran
doaj   +1 more source

Co-dynamics of hepatitis B and C viruses under the influence of CTL immunity

open access: yesAlexandria Engineering Journal
Understanding the cytotoxic T lymphocyte (CTL) immune response against hepatitis B virus (HBV) and hepatitis C virus (HCV) infections is crucial, as these infections can lead to liver cirrhosis and cancer. Mathematical models provide valuable support for
A.M. Elaiw   +3 more
doaj   +1 more source

The role of asymptomatic cattle for leptospirosis dynamics in a herd with imperfect vaccination

open access: yesScientific Reports
Leptospirosis is an emerging zoonotic disease with high health and economic damage. In this study, we developed a deterministic mathematical model that describes the dynamics of leptospirosis transmission within a cattle herd, incorporating asymptomatic ...
Abebe Girma Regassa   +1 more
doaj   +1 more source

Stability of generalized models for HIV-1 dynamics with impaired CTL immunity and three pathways of infection

open access: yesFrontiers in Applied Mathematics and Statistics
Highly active antiretroviral therapy (HAART) stands out as the most effective treatment for human immunodeficiency virus type-1 (HIV-1). While total eradication is still difficult, HAART can dramatically lower the virus's plasma viral level below the ...
Noura H. AlShamrani   +2 more
doaj   +1 more source

Optimal control efforts to reduce the transmission of HPV in a fractional-order mathematical model

open access: yesBoundary Value Problems
Human papillomavirus (HPV) is a sexually transmitted virus that causes cervical cancer in women and leads to death. In this research paper, we prepare a fractional mathematical model that contains a system of four fractional differential equations (FDEs)
A. El-Mesady   +2 more
doaj   +1 more source

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