Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Integrating artificial intelligence with circulating tumor DNA for non-small cell lung cancer: opportunities, challenges, and future directions. [PDF]
Thalambedu N+6 more
europepmc +1 more source
ADRENALINE SENSITIVITY OF PERIPHERAL BLOOD VESSELS IN HUMAN HYPERTENSION [PDF]
R. S. Duff
openalex +1 more source
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach+8 more
wiley +1 more source
A STABLE CUVETTE OF HIGH SENSITIVITY FOR INDICATOR DILUTION CURVES
John D. Van Norman
openalex +1 more source
THE SENSITIVITY OF THE TURTLE'S EAR AS SHOWN BY ITS ELECTRICAL POTENTIALS [PDF]
Ernest Glen Wever, Jack Vernon
openalex +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
Behavior of test specificity under an imperfect gold standard: findings from a simulation study and analysis of real-world oncology data. [PDF]
Walker MS, Slipski L, Natanzon Y.
europepmc +1 more source
The anaerobic cocci: gas formation, fermentation reactions, sensitivity to antibiotics and sulphonamides. Classification [PDF]
Ronald Hare+3 more
openalex +1 more source
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul+11 more
wiley +1 more source