Results 251 to 260 of about 10,108,798 (388)

Human gut microbes impact host serum metabolome and insulin sensitivity

Nature, 2016
H. Pedersen, Valborg Gudmundsdottir, H. Nielsen, Tuulia Hyotylainen, T. Nielsen, B. Jensen, K. Forslund, F. Hildebrand, Edi Prifti, G. Falony, E. Chatelier, F. Levenez, J. Doré, I. Mattila, D. Plichta, Päivi Pöhö, L. Hellgren, Manimozhiyan Arumugam, S. Sunagawa, S. Vieira-Silva, T. Jørgensen, J. Holm, K. Trošt, MetaHIT consortium, K. Kristiansen, S. Brix, J. Raes, Jun Wang, T. Hansen, P. Bork, S. Brunak, M. Orešič, S. Ehrlich, O. Pedersen   +33 more
semanticscholar   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

What Is Gestational Diabetes-Really? [PDF]

Diabetes
Buchanan TA, Xiang AH, Page KA, Watanabe RM.   +3 more
europepmc   +1 more source

The absolute sensitivity and functional stability of the human eye

, 1954
E. J. Denton, M. H. Pirenne
openalex   +2 more sources

Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors

Molecular Oncology, EarlyView.
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley   +1 more source

The spectral sensitivity of the pigeon's retinal elements

, 1953
K. O. Donner
openalex   +2 more sources

A Study of Sensitivity toHemophilus pertussisin Laboratory Animals [PDF]

, 1947
I. A. Parfentjev, M. A. Goodline, M. E. Virion   +2 more
openalex   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Impact of positive control binding properties on anti-drug antibody assay performance. [PDF]

Bioanalysis
Arceo T, Andrews B, Getz J, Haile S, Maia M, Song Y.   +5 more
europepmc   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source