Results 211 to 220 of about 29,659,346 (383)

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Sensitivity analysis of a mathematical model of Alzheimer's disease progression unveils important causal pathways. [PDF]

Front Neuroinform
Moravveji S, Sadia H, Doyon N, Duchesne S.   +3 more
europepmc   +1 more source

Sensitivity Analysis of Various Cost Elements in Flexible Pavement Design

, 1972
Eldon Yoder, Farideh Ramjerdi, W L Grecco   +2 more
openalex   +2 more sources

Sensitivity analysis via likelihood ratios [PDF]

, 1986
Martin I. Reiman, Alan Weiss
openalex   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Sensitivity and specificity of the hydrogen breath-analysis test for detecting malabsorption of physiological doses of lactose. [PDF]

, 1983
J L Rosado, Noel W. Solomons
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Enzymatic Synthesis of Amoxicillin in a Batch Reactor: Mathematical Modeling, Sensitivity Analysis, and Experimental Validation. [PDF]

ACS Omega
Martins Neto AP, Tavares ALS, Formigosa LF, Gomes BD, Gonçalves LRB, Viegas BM.   +5 more
europepmc   +1 more source

Study on Trace Analysis of Iron and Steel by Solid Mass Spectrography(II).On Precision, Relative Sensitivities and Analytical Results by Spark Source Mass Spectrograph

, 1970
Naoharu YAMAGUCHI, Ryoichi Suzuki
openalex   +2 more sources

Shape sensitivity analysis of flutter response of a laminated wing [PDF]

, 1989
Rakesh K. Kapania, Frederick D'Oench Bergen, Jean‐François Barthélémy   +2 more
openalex   +1 more source