Results 241 to 250 of about 2,651,129 (312)

Sensitivity analysis of unsafe behaviors in the spinning and weaving factories: Exploring the association with burnout and resilience using Bayesian networks. [PDF]

PLoS One
Azimi R, Al Sulaie S, Yazdanirad S, Khoshakhlagh AH, Cousins R, Kazemian F.   +5 more
europepmc   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Chaos control and sensitivity analysis of climate change under green gases and carbon omission utilizing caputo fractional operator. [PDF]

Sci Rep
Ahmad A, Khan MS, Ozsahin DU, Ahmad H, Munir A, Radwan T.   +5 more
europepmc   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Are AI weather models learning atmospheric physics? A sensitivity analysis of cyclone Xynthia. [PDF]

NPJ Clim Atmos Sci
Baño-Medina J, Sengupta A, Doyle JD, Reynolds CA, Watson-Parris D, Monache LD.   +5 more
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Key influencers in an aneurysmal thrombosis model: A sensitivity analysis and validation study. [PDF]

APL Bioeng
Liu Q, Lassila T, Lin F, MacRaild M, Patankar T, Islim F, Song S, Xu H, Chen X, Taylor ZA, Sarrami-Foroushani A, Frangi AF.   +11 more
europepmc   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Directional sensitivity analysis of the cerebral pressure-flow relationship during normothermia and moderate hyperthermia. [PDF]

J Appl Physiol (1985)
Taghizadeh M, Brothers RM, Labrecque L, Roy MA, Gagnon D, Smirl JD, Crandall CG, Brassard P.   +7 more
europepmc   +1 more source