Results 241 to 250 of about 29,659,346 (383)

Local and global sensitivity analysis for a prediction model of nitrogen loss in Southern China's paddy fields via HYDRUS-1D. [PDF]

Sci Rep
Wang S, Tong J, Huang C.
europepmc   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Sensitivity analysis for time-to-event data accounting for intra-individual variability in time-varying covariates with missing data. [PDF]

Sci Rep
Liaqat M, Chiapella L, Mishra P, Emam W, Tashkandy Y, Matuka A.   +5 more
europepmc   +1 more source

SensRORing cholesterol to drive protumoral myelopoiesis

Molecular Oncology, EarlyView.
Bleve et al. uncover a cholesterol‐driven immune evasion pathway, where RORγ‐dependent myelopoiesis shapes tumor immunosuppression. Targeting RORγ and PCSK9 emerges as a strategy to boost cancer immunotherapy. Protumoral myelopoiesis is a determinant of immunoevasion and tumor spread in many malignancies.
Sara Gennari, Luigi Nezi, Teresa Manzo
wiley   +1 more source

Pathogen distribution and antibiotic sensitivity analysis in urosepsis associated with urinary stones: A retrospective observational study. [PDF]

Medicine (Baltimore)
Hu Y, Wang X, Chen Y, Li J, Zhong Y, Zhu F, Yuan Y, Ye J, Yang F.   +8 more
europepmc   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Global sensitivity analysis of structural seismic demand based on information entropy. [PDF]

Sci Rep
Wang X, Xu Z, Sun C.
europepmc   +1 more source

Visual analysis of sensitivity in CAT models: interactive visualisation for CAT model sensitivity analysis [PDF]

Clouston, D., Dykes, J., Foote, M., Slingsby, A., Wood, J.   +4 more
core  

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Study on the mechanism of mining-induced pressure mitigation in gangue backfill mining and the sensitivity analysis of main controlling factors. [PDF]

PLoS One
Zhu L, Xu Y, Liu C, Zhou Y, Gu W, Zhu C, Liu Z.   +6 more
europepmc   +1 more source