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Sensitivity, Specificity, and Predictive Values in the 'Sensitivity and Specificity of Clinical Diagnostics'

JAMA: The Journal of the American Medical Association, 1989
To the Editor.— There was a confusing explanation of sensitivity and specificity in the article by Anderson et al 1 in the March 17 issue. Assuming proper use of the terms true positives, true negatives, false positives , and false negatives , sensitivity and specificity are defined correctly in the "Methods" section and in the footnote to Table 1 ...
B. A. Woodruff, R. C. Baron
  +4 more sources

Sensitivity and Specificity of a Weight Distribution Platform for the Detection of Objective Lameness and Orthopaedic Disease

Veterinary and comparative orthopaedics and traumatology, 2018
Introduction Weight distribution and off-loading at the stance are commonly used subjective assessments during the orthopaedic examination. The clinical relevance, sensitivity and specificity of limb off-loading have not yet been established.
W. Clough   +4 more
semanticscholar   +1 more source

Are Specific Allergen Sensitivities Inherited?

Current Allergy and Asthma Reports, 2010
A family history of an allergic condition is a well-accepted risk factor for the development of an allergic condition in an individual, particularly for allergic disorders such as asthma, eczema, and allergic rhinitis. However, the question of whether specific allergen sensitization is inherited requires a complicated answer, as environmental exposure ...
Rana Tawil, Misiak   +2 more
openaire   +2 more sources

Sensitivity and Specificity of a Monitoring Test

Biometrics, 1985
The usefulness of a diagnostic test is generally assessed by calculating the sensitivity and specificity, or the predictive value positive and predictive value negative of the test. When subjects are monitored periodically for evidence of disease, these calculations must incorporate the varying amounts of information per individual. If in addition, the
E R, DeLong, W B, Vernon, R R, Bollinger
openaire   +2 more sources

Sensitivity and specificity for correlated observations

Statistics in Medicine, 1992
AbstractA general estimating equation approach is used to obtain estimates of sensitivity and specificity when the data consist of correlated binary outcomes. First order approximations to the variances of estimated sensitivity and specificity for prospective and retrospective studies are given.
P J, Smith, A, Hadgu
openaire   +2 more sources

Lead Systems: Sensitivity and Specificity

Cardiology Clinics, 1984
In this article, the modified 12-lead system and the bipolar lead systems are discussed, both of which may provide adequate sensitivity and specificity of stress tests for clinical purposes. A single lead V5 or, preferably, bipolar modification of lead V5 may be adequate in certain situations in which cost or the type of population being tested ...
I L, Pina, R A, Chahine
openaire   +2 more sources

The sensitivity and specificity of MRI in stroke

Neurology, 1987
We compared MRI and CT in a study of 175 patients; 87 infarcts within a week, 40 from 1 to 40 weeks, 25 a year after onset, and 23 hemorrhages, 18 within 2 weeks and 5 in 4 to 8 weeks. Fifty-nine infarcts and eight hemorrhages had sequential scanning. MRI is more sensitive than CT in the early detection of cerebral infarcts.
A, Kertesz   +3 more
openaire   +2 more sources

Sensitivities and Specificities of Diagnostic Tests

JAMA: The Journal of the American Medical Association, 1982
To the Editor.— The article by Harris on "The Hazards of Bedside Bayes" (1981;236:2602) presents an important caution. However, it misrepresents the inherent variability in data on diagnostic tests that can be collected in well-designed studies, and may exaggerate the effective variability of data on tests now in the literature.
openaire   +2 more sources

Sensitive and specific CRISPR diagnostics

Science, 2017
CRISPR Technology Methods are needed that can easily detect nucleic acids that signal the presence of pathogens, even at very low levels. Gootenberg et al. combined the allele-specific sensing ability of CRISPR-Cas13a with recombinase polymerase amplification methods to detect specific RNA and DNA sequences.
openaire   +2 more sources

Sensitivity, Specificity, and Vaccine Efficacy

Controlled Clinical Trials, 1998
We study the effects of imperfect sensitivity and specificity on estimation of vaccine efficacy (VE). We show that a specificity of
openaire   +2 more sources

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