Genetic diversity in <i>Eimeria</i> species infecting chickens: Implications for virulence, host immunity, vaccine performance, anticoccidial drug sensitivity and diagnostic reliability. [PDF]
Rafeer NM, Adeleke MA.
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
The Value of the Dual Systems Model of Adolescent Risk-Taking
Nicole Marie Strang +2 more
doaj +1 more source
The social brain in the classroom: insights from the SELF study on neural correlates of adolescent motivation, belonging, and learning. [PDF]
Raufelder D, Hoferichter F.
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Evaluation and comparison of three qPCR commercial assays and three automated platforms for the detection of monkeypox virus DNA. [PDF]
Usal M +8 more
europepmc +1 more source
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Sensitivity-based Warmstarting for Constrained Model Predictive Control
Model predictive control (MPC) is of increasing interest in applications for constrained control of multivariable systems. However, one of the major obstacles to its broader use is the computation time and effort required to solve a possibly non-convex ...
Veliov, Vladimir +4 more
core
Revisiting the potential of upconversion nanoparticles in biomedical applications: Advances and emerging perspectives. [PDF]
Ghorbanizamani F +3 more
europepmc +1 more source
Control of delay systems for minimax sensitivity.
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 1986 ; Vita. ; Bibliography: leaves 161-162. ; by David S. Flamm. ; Ph. D. ; Ph. D.
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