Results 31 to 40 of about 976,271 (267)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

An integrodifferential approach to modeling, control, state estimation and optimization for heat transfer systems

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2016
In this paper, control-oriented modeling approaches are presented for distributed parameter systems. These systems, which are in the focus of this contribution, are assumed to be described by suitable partial differential equations.
Rauh Andreas   +4 more
doaj   +1 more source

Sensitivity Analysis for Voltage Stability Considering Voltage Dependent Characteristics of Loads and DGs

open access: yesIEEE Access, 2021
The sensitivity analysis becomes particularly critical for voltage stability analysis due to the fluctuation in power outputs of renewable energy resources.
Khaled Alzaareer   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Frequency control strategy for coordinated energy storage system and flexible load in isolated power system

open access: yesEnergy Reports, 2022
The isolated power system has a simple structure with small inertia and no support from the large-scale power system, so the frequency stability problem is more prominent. A frequency control method based on coordinated control of flexible loads (FL) and
Jie Yu, Siyang Liao, Jian Xu
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

IDENTIFICATION OF REFUSALS OF CONTROL SYSTEMS OF AIRCRAFTS BY MEANS OF SENSITIVITY FUNCTIONS

open access: yesНаучный вестник МГТУ ГА, 2016
Article is devoted to detection and identification of refusals of governing bodies like "withdrawal and a klineniye" in ideal statement (the atmosphere - not indignant, sensors - ideal). Relevance of consideration of the matters is caused by a problem of
A. D. Barabash, I. N. Merzlikin
doaj  

Quantification and Mitigation of Unfairness in Active Power Curtailment of Rooftop Photovoltaic Systems Using Sensitivity Based Coordinated Control

open access: yesEnergies, 2016
With increasing photovoltaic (PV) penetration in low voltage networks (LVNs), voltage regulation is a challenge. Active power curtailment (APC) is one possible solution for mitigating over voltages resulting from active power injection in LVNs.
Aadil Latif   +2 more
doaj   +1 more source

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