Results 221 to 230 of about 92,833 (358)

Validity of methods to predict the respiratory sensitizing potential of chemicals: A study with a piperidinyl chlorotriazine derivative that caused an outbreak of occupational asthma.

Toxicological Sciences, 2003
J. Vanoirbeek, C. Mandervelt, A. Cunningham, P. Hoet, Haiyan Xu, H. Vanhooren, B. Nemery   +6 more
semanticscholar   +1 more source

FGF21 targets pathways which enhance insulin sensitivity in brown adipose but not skeletal muscle in mice.

Endocrinology
Juber MC, King-McAlpin S, Buscaglia P, Sebag JA, Potthoff MJ.   +4 more
europepmc   +1 more source

Acquired CCDC6-RET Fusion After First-Line Osimertinib in Epidermal Growth Factor Receptor (EGFR)-Mutant Lung Adenocarcinoma: A Case Report. [PDF]

Cureus
Afonso ARS, Nascimento L, Cruz M, Gomes T, Conde B.   +4 more
europepmc   +1 more source

Bidirectional Photoswitching of a Tailored Azobenzene with Red and Far‐Red Light Involving Triplet Sensitization in an Aqueous System

Advanced Science, EarlyView.
The action spectrum of a tailored azobenzene is shifted toward bio‐optical window through the chemical modification of its singlet and triplet energy levels. Consequently, the bidirectional photo‐switching of azobenzene in physiological conditions is achieved when excited by red and far‐red light, which offers greater tissue penetration.
Mila Miroshnichenko, Helen Hölzel, Edvinas Orentas, Karolis Kazlauskas, Pedro Ferreira, Fabienne Dumoulin, Carles Alcaide, Miquel Solà, Roger Bresolí‐Obach, Santi Nonell, Pankaj Bharmoria, Kasper Moth‐Poulsen   +11 more
wiley   +1 more source

βKlotho is required for fibroblast growth factor 21 effects on growth and metabolism.

Cell Metabolism, 2012
Xunshan Ding, Jamie Bonéy-Montoya, B. Owen, A. Bookout, K. Coate, D. Mangelsdorf, S. Kliewer   +6 more
semanticscholar   +1 more source

Insulin resistance induced by obesity: Mechanisms, metabolic implications and therapeutic approaches. [PDF]

Mol Biol Rep
Choo YN, Ravi RN, Subramaniyan V.
europepmc   +1 more source

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

Advanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu, Fan Wei, Chi Woo Yoon, Qifa Zhou, Yingxiao Wang   +4 more
wiley   +1 more source

Dissection of the insulin-sensitizing effect of liver X receptor ligands.

Molecular Endocrinology, 2007
S. Commerford, Leo Vargas, Suzanne E. Dorfman, N. Mitro, N. Mitro, Erik C. Rocheford, P. A. Mak, Xue Li, P. Kennedy, Tara L Mullarkey, E. Saez, E. Saez   +11 more
semanticscholar   +1 more source

Twelve weeks of voluntary wheel running restores glucagon sensitivity in middle-aged mice. [PDF]

Am J Physiol Endocrinol Metab
Marx TJ, Bruner KR, Ghimire S, Fletcher T, Vasileva A, Stern JH.   +5 more
europepmc   +1 more source

Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation

Advanced Science, EarlyView.
Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang, Zenghui Cui, Yunkai Zhang, Zhiqing Li, Xuetao Cao   +4 more
wiley   +1 more source