Results 81 to 90 of about 3,269,240 (334)

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

FEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa, Cong Lin, Irina A. Talyzina, Marina V. Goncharuk, Eduard V. Bocharov, Alexander S. Arseniev, Xiaohui Wang, Sergey A. Goncharuk, Konstantin S. Mineev   +8 more
wiley   +1 more source

Efficient calculation of sensor utility and sensor removal in wireless sensor networks for adaptive signal estimation and beamforming [PDF]

, 2012
Wireless sensor networks are often deployed over a large area of interest and therefore the quality of the sensor signals may vary significantly across the different sensors.
Bertrand, Alexander, Moerman, Ingrid, Moonen, Marc, Ruckebusch, Peter, Szurley, Joseph   +4 more
core   +2 more sources

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Identification of NLOS and Multi-Path Conditions in UWB Localization Using Machine Learning Methods

Applied Sciences, 2020
In ultra-wideband (UWB)-based wireless ranging or distance measurement, differentiation between line-of-sight (LOS), non-line-of-sight (NLOS), and multi-path (MP) conditions is important for precise indoor localization.
Cung Lian Sang, Bastian Steinhagen, Jonas Dominik Homburg, Michael Adams, Marc Hesse, Ulrich Rückert   +5 more
doaj   +1 more source

Real-time complex light field generation through a multi-core fiber with deep learning

Scientific Reports, 2022
The generation of tailored complex light fields with multi-core fiber (MCF) lensless microendoscopes is widely used in biomedicine. However, the computer-generated holograms (CGHs) used for such applications are typically generated by iterative ...
Jiawei Sun, Jiachen Wu, Nektarios Koukourakis, Liangcai Cao, Robert Kuschmierz, Juergen Czarske   +5 more
doaj   +1 more source

Photoelasticity based dynamic tactile sensor [PDF]

, 2005
The paper presents design, construction and testing of a photoelasticity based dynamic sensor which is capable of detecting slip as well as providing normal force information.
Crowder, Richard M., Dubey, Venketesh N.
core   +1 more source

Environmental sensors and networks of sensors

Sensor Review, 2008
Environmental sensors and networks of sensors are transforming everyday life by scrutinizing our environment and sometimes feeding into control systems that then adjust our environment to improve our processes and lives.
openaire   +3 more sources

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source