Results 91 to 100 of about 12,049,870 (288)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Design study of a thermocouple power sensor as a monolithic fin-line [PDF]
, 2011 Making traceable power measurements above 110 GHz using current measurement technologies is challenging. We investigate a design of power sensor consisting of a thermocouple-based integrated circuit (IC) mounted as a finline component in WR-6 waveguide ...
Jonathan Scott +3 more
core +1 more source
Methods for reducing the temperature error of pressure sensors
Технологія та конструювання в електронній апаратурі, 2002 The paper analyzes the temperature errors of pressure sensors and reveals the physical nature of their occurrence. Recommendations for designing pressure sensors with reduced temperature error are developed.
V. A. Vasilyev
doaj
Sensors, 2018 This work focuses on the proof-mass mechanical structural design improvement of a tri-axial piezoresistive accelerometer specifically designed for head injuries monitoring where medium-G impacts are common; for example, in sports such as racing cars or ...
Marco Messina +2 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Investigation of Interferences of Wearable Sensors with Plant Growth
BiosensorsPlant wearable sensors have shown exceptional promise in continuously monitoring plant health. However, the potential adverse effects of these sensors on plant growth remain unclear.
Xiao Xiao +7 more
doaj +1 more source
Magnetoelectric Current Sensors
Sensors, 2017 In this work a magnetoelectric (ME) current sensor design based on a magnetoelectric effect is presented and discussed. The resonant and non-resonant type of ME current sensors are considered.
Mirza Bichurin +4 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source