Results 61 to 70 of about 210,346 (266)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Advances in Optical Fiber Sensors for Multi-Analyte Biochemical Detection
BiosensorsOptical fiber multi-analyte biosensors have become an important cutting-edge technology for the simultaneous detection of multiple biochemical substances in complex samples due to their unique advantages such as small size, anti-interference capability ...
Jianwei Huang +3 more
doaj +1 more source
Probability Model Based Coverage-Enhancing Algorithm for WSNs of Nodes' Adjustable Movement Pattern
International Journal of Distributed Sensor Networks, 2012 Aimed at the defects of current coverage-enhancing algorithms, firstly the probability model is introduced into the coverage-enhancing algorithm of the directional sensor network based on the virtual potential field, and the probability model would have ...
Junjie Huang +4 more
doaj +1 more source
Type-2 Fuzzy Sliding Mode Anti-Swing Controller Design and Optimization for Overhead Crane
IEEE Access, 2018 Overhead crane is regarded as a kind of complex nonlinear dynamic system in which the underactuated characteristic makes the controller hardly control the space of load swing effectively.
Zhe Sun +5 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Wireless sensor networks [PDF]
IEEE Wireless Communications, 2004 Havinga, Paul J.M. +2 more
openaire +3 more sources
Online Spectrum Prediction With Adaptive Threshold Quantization
IEEE Access, 2019 In this paper, we explore the spectrum inference to achieve the spectrum occupancy in advance through analyzing the historical spectrum. We have conceived an offline-online cooperative framework.
Haoyu Li +4 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source