Results 51 to 60 of about 3,801,030 (293)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Yirmi yıldan uzun süredir, pek çok yeni iletişim teknolojisinin ortaya çıkışına şahit olunmaktadır. Bunlar arasında, ağ ,optik, kızılötesi ve bluetooth örnek gösterilebilir. Pekçok araştırmacı bu konuya , bu teknolojilerin acil durumlarda kullanılması ile alanlara, özellikle de ev, ofis, klinik, fabrika, ulaşım araçları, küresel çevre ve yangın ...
openaire +2 more sources
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Environmental Sensor Networks: a revolution in the earth system science? [PDF]
Environmental Sensor Networks (ESNs) facilitate the study of fundamental processes and the development of hazard response systems. They have evolved from passive logging systems that require manual downloading, into ‘intelligent’ sensor networks that ...
Martinez, Kirk +3 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Self-organising Sensor networks. [PDF]
Sensor Networks consist of a large number of low-cost low-power devices, each with sufficient hardware to monitor one or more variables and send and receive the readings for these variables to other devices.
Roadknight, Chris +5 more
core
PMSM integral sliding mode control based on improved power exponential reaching law
Permanent magnet synchronous motors are highly coupled, multivariable, and nonlinear, and sliding mode control has gradually gained traction in motor control systems due to its robustness.
Weilai Shang, Hengqiang Wang
doaj +1 more source
Environmental Sensor Networks [PDF]
This report is based on the 2004 AGU Fall Meeting's session entitled “Special Focus: Advances in Data Acquisition, Management, Analysis and Display: Cyberinfrastructure for Earth Systems Science IV: Sensor Networks.”An environmental sensor network comprises an array of sensors that gather data autonomously and automatically forward the data to a ...
Jane K. Hart, Kirk Martinez
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

