Results 131 to 140 of about 87,827 (343)

Clinical and genetic characteristics of Cornelia de Lange syndrome in pediatric patients

open access: yesPediatric Investigation, EarlyView.
NIPBL variants (78.9%) dominate 19 Chinese pediatric Cornelia de Lange syndrome (CdLS). Universal craniofacial anomalies (94.7%) and developmental delay (84.2%) were observed. NIPBL null variants are associated with severe growth impairment and microcephaly, yet overall clinical severity remains heterogeneous, underscoring genotype‐phenotype complexity
Xiaoqiao Li   +10 more
wiley   +1 more source

Update on Gene Therapy in the Treatment of Hereditary Hearing Loss

open access: yesSensory Neuroscience, EarlyView.
Gene therapy is a promising therapeutic approach for genetic disorders, including three major gene therapy strategies: gene replacement, gene suppression, and gene editing. After transmitting genes to the inner ear through appropriate pathways, repair the cochlea in order to achieve the goal of treating hereditary hearing loss.
Weiwei He   +7 more
wiley   +1 more source

Constraint Induced Neglect Therapy (CINT): A Proposed Technique for Spatial Neglect Rehabilitation in Patients With Stroke

open access: yesSensory Neuroscience, EarlyView.
ABSTRACT Effective rehabilitation techniques for neglect are lacking. The aim of this article is to propose a method in which a comfortable sound that is convenient to the hearing of patients with stroke will be delivered to the affected side's ear via a head phone for 6 h a day divided in 3 sessions (2 h each) per day, for 2 weeks to improve neglect ...
Auwal Abdullahi   +2 more
wiley   +1 more source

Determinant of chronic suppurative otitis media and its association with the sensorineural component of hearing loss

open access: yesJournal of Indira Gandhi Institute of Medical Sciences
Background: Chronic suppurative otitis media (CSOM) is a leading disorder known for hearing loss. We aimed to investigate the associated determinant factors of CSOM with sensorineural hearing loss (SNHL).
Shruti Jha, Rakesh Kumar Singh
doaj   +1 more source

Adult‐Onset Dystonia‐Parkinsonism: Do Not Forget SERAC1

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Giulia Scacciatella   +15 more
wiley   +1 more source

Conductive Materials and Electrical Stimulation for Auditory Restoration

open access: yesSensory Neuroscience, EarlyView.
Applications of electroconductive biomaterials and electrical stimulation in cochlear tissue engineering.(1) Enable auditory neural repair through conductive materials and electrical stimulation, enhancing neuron survival and synaptic plasticity.(2) Integrate optogenetic‐electrical systems and cochlear organoid platforms for frequency‐specific ...
Menghui Liao   +8 more
wiley   +1 more source

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