Results 41 to 50 of about 30,581 (134)
The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges
Advanced Science, EarlyView.This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li +3 more
wiley +1 more source
Rational Design of Inner Ear Drug Delivery Systems
Advanced Science, EarlyView.Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu +5 more
wiley +1 more source
Sensorineural Hearing Impairment is a Common Feature of Consanguineous Marriage [PDF]
, 2009 Introduction: Sensorineural hearing loss (SNHL) accounts for about 60% of all hearing loss. This is sometimes also called “Nerve deafness”. The term “Sensorineural” is used to indicate that there is either a cochlear or an eight nerve lesion.
El-Din, SMN, Hamed, L
core +1 more source
Sensorineural Hearing Loss due to Air Bag Deployment [PDF]
, 2012 Deployment of the air bag in a passenger vehicle accident rarely causes otologic injuries. However, sensorineural hearing loss induced by air bag deployment is extremely rare, with only a few cases reported in the English literature.
Ishikawa, Jyunichi +2 more
core +1 more source
Multicargo Porous Cochlear Electrode Coating for Antifibrosis After Cochlear Implantation
Advanced Science, EarlyView.This study presents a novel porous drug‐loading coating for cochlear electrodes, utilizing MA‐PDMS infused with GelMA hydrogel containing dexamethasone and MXene nanoparticles. The coating enhances biocompatibility, enables sustained drug release, reduces fibrosis, and preserves residual hearing post‐CI.
Lei Ren +15 more
wiley +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Advanced Science, EarlyView.Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang +4 more
wiley +1 more source
Hearing Loss in Infectious and Contagious Diseases [PDF]
, 2015 Hearing loss can occur for various reasons, whether it is of a genetic, congenital or acquired character. Infectious diseases stand out among those causing this type of deficiency and account for approximately 25% of all cases of profound hearing loss ...
Alves Leitão, Paula Cristina +3 more
core +2 more sources
Advanced Science, EarlyView.Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai +14 more
wiley +1 more source
Visualization of the Spiral Ganglion Neuron in Vivo Using a Novel 177Lu Nuclear Molecule Label
Advanced Science, EarlyView.The study developed and validated a radionuclide‐labeled anti‐VGLUT1 antibody probe for the first nuclear imaging of cochlear spiral ganglion neurons (SGNs) in vivo. This approach may provide aid in screening candidates suitable for CI surgery by quantifying the number of surviving SGNs, and predicting the potential for postoperative hearing ...
Chenyang Kong +11 more
wiley +1 more source
Advancements in Treatment for Sensorineural Hearing Loss: Implications for Rehabilitation Professionals [PDF]
, 2015 Rehabilitation professionals often work with individuals with sensorineural hearing loss. Sometimes the hearing loss is due to ototoxic medications that are prescribed as treatments for other conditions.
Cruz, Bianca +3 more
core +2 more sources