Results 181 to 190 of about 1,302,851 (299)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Optical Fiber pH and Dissolved Oxygen Sensors for Bioreactor Monitoring: A Review. [PDF]

Sensors (Basel)
Cui G, Wu R, Cao L, Abedin S, Goel K, Yoon S, Wang X.   +6 more
europepmc   +1 more source

An Intrusion Detection Architecture Based on the Energy Consumption of Sensors Against Energy Depletion Attacks in LoRaWAN

André Proto, Charles C. Miers, Tereza Cristina Melo de Brito Carvalho   +2 more
openalex   +1 more source

Biochemical sensing with a polymer-based micromachined Fabry-Perot sensor

, 2010
Tianhua Zhang, S. A. Ouambo Talla, Zhongcheng Gong, Sukrut Karandikar, Rebecca Giorno, Long Que   +5 more
openalex   +1 more source

Disruption of the dimerization interface of the sensing domain in the dimeric heme-based oxygen sensor AfGcHK abolishes bacterial signal transduction [PDF]

, 2019
Tereza Skálová, Alžběta Lengálová, Jan Dohnálek, Karl Harlos, Peter Mihalčin, Petr Kolenko, Martin Stráňava, Jan Bláha, Tôru Shimizu, Markéta Martínková   +9 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Surface Plasmon Resonance Sensors Based on the Molecularly Imprinted Technique for Simvastatin Detection. [PDF]

ACS Omega
Faalnouri S, Çimen D, Denizli A, Bereli N.   +3 more
europepmc   +1 more source

Development of a standard fall data format for signals from body-worn sensors

, 2013
Jochen Klenk, Lorenzo Chiari, Jorunn L. Helbostad, Wiebren Zijlstra, Kamiar Aminian, Chris Todd, Stefania Bandinelli, Ngaire Kerse, Lars Schwickert, Sabato Mellone, Fabio Bagalà, Kim Delbaere, Klaus Hauer, Stephen J. Redmond, Stephen N. Robinovitch, Omar Aziz, Michael Schwenk, Aleksandra Zecevic, Tania Zieschang, Clemens Becker   +19 more
openalex   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Robust Learning-Based Detection with Cost Control and Byzantine Mitigation. [PDF]

Sensors (Basel)
Zhong C, Gursoy MC, Velipasalar S.
europepmc   +1 more source