Results 121 to 130 of about 190,244 (278)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Higher sensory processing sensitivity: increased cautiousness in attentional processing in conflict contexts

Cognition and Emotion
While interest grows in investigating sensory processing sensitivity (SPS), few studies have employed objective behavioural measures to directly explore the underlying attentional processing. The present study utilised two modified versions of the Emotional Attention Networks Test Integration (E-ANTI) to investigate whether and how emotion interacts ...
Luchuan Xiao, Kris Baetens, Natacha Deroost   +2 more
openaire   +3 more sources

Relationship Between Sensory Profile and Academic Achievement in University Students: A Cross-Sectional Study

Üniversite Araştırmaları Dergisi
This study aimed to examine the relationship between sensory profile and academic achievement in university students. This cross sectional study was conducted with 252 university students (80 female and 172 male).
Müşerrefe Nur Keleş
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

The Assessment of Cognitive Emotion Regulation Strategies, Sensory Processing Sensitivity and Anxiety Sensitivity in Patients with Multiple Sclerosis

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2016
Background: The purpose of this study was to compare the cognitive emotional regulation strategies, sensory processing sensitivity and anxiety sensitivity in patients with multiple sclerosis and normal people.
Esmeil Soleymani, Mojtaba Habibi, Emrah Tajoddini   +2 more
doaj  

The impact of physical exercise on the flourishing level of vocational college students: an analysis based on random forest regression algorithm and moderated mediation model

Frontiers in Public Health
This study examined the associations among physical exercise, sensory processing sensitivity, depression–happiness, relational energy, and flourishing in vocational college students, with a focus on the serial mediating roles of sensory processing ...
Fan-Zheng Mu, Ming-Jia Li, Li-Han Lin, Rui Chen, Zan Huang, Hu Lou, Sai Zhu, Jian-hua Xu   +7 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

The Interaction between Sensory Processing Sensitivity and Childhood Environment on Social Anxiety

, 2016
It is known that high sensory processing sensitivity can lead to positive or negative outcomes, depending partly on the childhood environment. It is also known that there is a link between high sensory processing sensitivity and social anxiety.
Jaswetz, Lars
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

High Sensitivity to Interpersonal Interaction: Development of a Measurement

Psychologica Belgica
Interpersonal sensitivity is an aspect of Sensory Processing Sensitivity (SPS) that has been unexplored precisely despite potentially playing an even more significant role in individuals with SPS.
Karina Salud Montoya-Pérez, Ferran Padrós-Blázquez, Rocío Montoya-Pérez   +2 more
doaj   +1 more source