Results 151 to 160 of about 124,753 (243)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Correction to "Assessment of Central Sensitivity Syndrome and Sensory Processing Sensitivity: A Systematic Review". [PDF]

Ann N Y Acad Sci
europepmc   +1 more source

The Moderating Role of Sensory Processing Sensitivity in Social Skills Enhancement and Bullying Prevention Among Adolescents. [PDF]

Behav Sci (Basel)
Acevedo BP, Sperati A, Williams C, Griffin KW, Tork A, Botvin GJ.   +5 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Sensory processing sensitivity, anxiety, and short-term heart rate variability in older adults living at high southern latitudes: a brief report. [PDF]

Front Psychiatry
Baeza D, Huirimilla-Casanova L, Estrada C, Buccella S, Castillo-Aguilar M, Núñez-Espinosa C.   +5 more
europepmc   +1 more source

Demographic profile of Sensory Processing Sensitivity

Personality and Individual Differences
María Luz Morales-Botello, Moisés Betancort, Manuela Pérez-Chacón, Rosa-María Rodríguez-Jiménez, Antonio Chacón   +4 more
openaire   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Painfully Sensitive: How Sensory Processing Sensitivity Affects Healthy Adolescents' Perception of Pain. [PDF]

J Pain Res
Hochreuter J, Wehrli S, Locher C, Lionetti F, Kossowsky J, Pluess M, Koechlin H.   +6 more
europepmc   +1 more source