Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Tasting with Feelings: Socioeconomic Differences in Children's Emotional and Sensory Description of Vegetables. [PDF]
FoodsEstay K, Escalona V, Escobar F.
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Exploring the Impact of Multimodal Training on Sensory, Motor and Cognitive Function Among Children with Attention Deficit Hyperactivity Disorder: A FOCUS Protocol of Randomised Controlled Trial. [PDF]
Ann NeurosciSharma N, Chahal A.
europepmc +1 more source
Metaphorical Expressions of Temperature Sensory Words in the Theory of Traditional Chinese Medicine
, 2016 Xiaoyuan Yang, Chunhua Jia
openalex +2 more sources
‘Online’ integration of sensory and fear memories
, 2020 Francesca S Wong +2 more
openalex +1 more source
TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
The Association Between the Occurrence of Sensory Integration Disorders, Depression, and Chronic Fatigue in Patients with Relapsing-Remitting Multiple Sclerosis. [PDF]
J Clin MedMachowska-Sempruch K +4 more
europepmc +1 more source