Results 221 to 230 of about 2,281,930 (436)

Internal sensory models allow for balance control using muscle spindle acceleration feedback [PDF]

open access: yesarXiv
Motor control requires sensory feedback, and the nature of this feedback has implications for the tasks of the central nervous system (CNS): for an approximately linear mechanical system (e.g., a freely standing person, a rider on a bicycle), if the sensory feedback does not contain the state variables (i.e., joint position and velocity), then optimal ...
arxiv  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Interdisciplinary Translations: Sensory Perception as a Universal Language [PDF]

open access: yesarXiv
This paper investigates sensory perception's pivotal role as a universal communicative bridge across varied cultures and disciplines, and how it manifests its value in the study of media art, human computer interaction and artificial intelligence. By analyzing its function in non-verbal communication through interactive systems, and drawing on the ...
arxiv  

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

Unified Beta Regression Model with Random Effects for the Analysis of Sensory Attributes [PDF]

open access: yesarXiv
Studies involving sensory analysis are essential for evaluating and measuring the characteristics of food and beverages, including consumer acceptance of samples. For various products, the experimental designs are generally incomplete block designs, with sensory attributes assessed using hedonic scales, ratings, or scores.
arxiv  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

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