Results 81 to 90 of about 117,891 (311)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

The effects of sensory deprivation on sensory, perceptual, motor, cognitive, and physiological functions [PDF]

open access: yes
Sensory deprivation effects on human sensory, perceptual, and physiological ...
Fisher, L.   +3 more
core   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Effect of sensory deprivation and locus coeruleus phasic electrical stimulation following the deflection of adjacent whisker on response properties of principal whisker related-neurons in layer IV of rat barrel cortex [PDF]

open access: yes
Background: Barrel cortex of rodents is responsible for sensory information processing via facial whiskers. Locus coeruleus (LC), main source of cortical norepinephrine (NE), influences tactile sensory processing.
آفرینش, محمدرضا   +4 more
core  

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Effects of congenital hearing loss and cochlear implantation on audiovisual speech perception in infants and children [PDF]

open access: yes, 2010
Purpose: Cochlear implantation has recently become available as an intervention strategy for young children with profound hearing impairment. In fact, infants as young as 6 months are now receiving cochlear implants (CIs), and even younger infants are ...
Bergeson, Tonya R.   +2 more
core   +2 more sources

Pyramidal Neurons in Different Cortical Layers Exhibit Distinct Dynamics and Plasticity of Apical Dendritic Spines

open access: yesFrontiers in Neural Circuits, 2017
The mammalian cerebral cortex is typically organized in six layers containing multiple types of neurons, with pyramidal neurons (PNs) being the most abundant.
Michelle Tjia   +4 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Brief guided imagery and body scanning interventions reduce food cravings [PDF]

open access: yes, 2013
mindfulness cognition food intrusive thoughts acceptance eatingElaborated Intrusion (EI) Theory proposes that cravings occur when involuntary thoughts about food are elaborated; a key part of elaboration is affectively-charged imagery.
Andrade, J   +4 more
core   +2 more sources

Phenomenology and interoception: Comment on Leder

open access: yesRivista Internazionale di Filosofia e Psicologia
Interoception is an important contributor to our everyday phenomenology. Two thought experiments can tell us something about the role it plays in our experience.
Shaun Gallagher
doaj   +1 more source

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