Results 61 to 70 of about 86,412 (250)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Frequency of Sensory Processing Disorders in Children Aged 5 to 11 Years Old

Journal of Mazandaran University of Medical Sciences, 2019
Background and purpose: Sensory processing is necessary to perform daily activities properly. The aim of this study was to investigate the frequency of sensory processing disorder in children aged 5-11 years old.
Navid Mirzakhani, Faezeh Dehghan, Marjan Shahbazi, Fatemeh Shahbazi   +3 more
doaj  

برنامج مقترح لتنمية المعالجة الحسية وتحسين التواصل لدى الأطفال ذوو اضطراب التوحد A proposed Program for Developing Sensory Processing and Enhancing Communication among Children with Autism Disorder [PDF]

Maǧallaẗ Al-I'ršād Al-Nafsī
مستخلص البحث: هدفت الدراسة إلى تقديم تصور لبرنامج تدخل مبكر لتنمية المعالجة الحسيه أثره على  التواصل لدى الأطفال ذوو اضطراب التوحد الذين تتراوح أعمارهم ما بين (6:4) سنوات، ويتكون البرنامج من (42) جلسة ، ركزت على 8 مجالات وهم ( المعالجة السمعية، المعالجة
محمد أحمد علي هيبة, زينب رضا كمال الدين, أميرة حلمي فهيم جرجس   +2 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The facilitators and barriers encountered by South African parents regarding Sensory Integration occupational therapy

South African Journal of Occupational Therapy, 2018
  Introduction: Differences in parent perceptions regarding occupational therapy using a sensory integration approach to treatment have been noted.
Jacintha Smit, Jo-Celene De Jongh, Ray Anne Cook   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Sensory Processing as a Predictor of Feeding/Eating Behaviors in Children with Autism Spectrum Disorder

Open Journal of Occupational Therapy, 2016
Background: Children with Autism Spectrum Disorder (ASD) frequently have feeding and eating difficulties as well as unusual responses to sensory stimuli. This can lead to significantly compromised occupational performance.
Jerilyn Smith
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Sensory Processing Challenges in Children with Neurodevelopmental Disorders and Genetic Conditions: An Observational Study

NeuroSci
Sensory processing challenges are crucial yet often neglected aspects in the care of children with neurodevelopmental disorders and genetic conditions. They represent a key area of interest in neuroscience, as they significantly impact children’s daily ...
Ekaine Rodríguez-Armendariz, María Vela-Romero, Adrián Galiana   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source