Results 91 to 100 of about 136,443 (290)

Characterizing Olfactory Function in Children with Autism Spectrum Disorder and Children with Sensory Processing Dysfunction [PDF]

, 2020
Julia Sweigert, Tanya St. John, K. Kawena Begay, Greg E. Davis, Jeffrey Munson, Eric G. Shankland, Annette Estes, Stephen R. Dager, Natalia M. Kleinhans   +8 more
openalex   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Sensory processing, praxis and related social participation of children with Down syndrome 5-12 years of age attending educational facilities in Bloemfontein, South Africa

South African Journal of Occupational Therapy, 2016
Background: Down syndrome is one of the most investigated and well discussed syndromes related to intellectual disability,  yet little can be found in literature of the impact that sensory processing difficulties or disorders have on the functioning of 
Annamarie van Jaarsveld, Francois C van Rooyen, Al-Mari van Biljon, Ilze Janse van Rensburg, Katherine James, Laetitia Boning, Lise Haefele   +6 more
doaj   +1 more source

Sensory Processing Disorders in Children and Adolescents: Taking Stock of Assessment and Novel Therapeutic Tools. [PDF]

Brain Sci, 2022
Passarello N, Tarantino V, Chirico A, Menghini D, Costanzo F, Sorrentino P, Fucà E, Gigliotta O, Alivernini F, Oliveri M, Lucidi F, Vicari S, Mandolesi L, Turriziani P.   +13 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The sensory dimension of attention deficit hyperactivity disorder: a case–control study on the impact of sensory profile on daily functioning among Turkish children with ADHD

Middle East Current Psychiatry
Background Sensory profile differences are commonly observed in children with Attention Deficit Hyperactivity Disorder (ADHD). This study aimed to examine the sensory profiles of children with ADHD, their impact on symptom severity, and their association
Begum Yulug Tas, Gonca Ozyurt, Oyku Yavuz Kan, Gozde Ulas   +3 more
doaj   +1 more source

Neurobehavior and MRI in 22ql3.3 Deletion Syndrome

Pediatric Neurology Briefs, 2008
Neuromotor, sensory, language, communication and social development, and cerebral MRI and PET studies were performed in 8 children with 22ql3.3 deletion syndrome, at the National Institutes of Health, Necker-Enfants Malades Hospital, and other centers in
J Gordon Millichap
doaj   +1 more source

Sensory Processing and Aggressive Behavior in Adults with Autism Spectrum Disorder [PDF]

, 2021
Frank van den Boogert, Bram Sizoo, Pascalle Spaan, Sharon Tolstra, Yvonne H. A. Bouman, Witte J.G. Hoogendijk, Sabine J. Roza   +6 more
openalex   +1 more source