Results 181 to 190 of about 23,169,120 (329)

Salmonid sensory system development is affected by climate change driven temperature increases. [PDF]

Sci Rep
Jones AE, O'Donnell MJ, Regish AM, Webb JF.   +3 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Ordered patterning of the sensory system is susceptible to stochastic features of gene expression. [PDF]

Elife, 2020
Giri R, Papadopoulos DK, Posadas DM, Potluri HK, Tomancak P, Mani M, Carthew RW.   +6 more
europepmc   +1 more source

Enteric nervous system: sensory transduction, neural circuits and gastrointestinal motility

Nature reviews: Gastroenterology & hepatology, 2020
N. Spencer, Hongzhen Hu
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Biomimetic Neuromorphic Sensory System via Electrolyte Gated Transistors. [PDF]

Sensors (Basel)
Li S, Gao L, Liu C, Guo H, Yu J.
europepmc   +1 more source

A survey of integration and fusion systems for multi-sensory information.

, 1990
G. Kinoshita
openalex   +2 more sources

Changes in the Escape Eliciting System of a Cricket Revealed by Sensory Deprivation during Postembryonic Development [PDF]

, 2001
Masamichi Kanou, M. Ureshi, Yasutaka Suematsu, Kenjiro Hirao   +3 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

A Multifunctional Tactile Sensory System for Robotic Intelligent Identification and Manipulation Perception. [PDF]

Adv Sci (Weinh)
Jiang Y, Fan L, Sun X, Luo Z, Wang H, Lai R, Wang J, Gan Q, Li N, Tian J.   +9 more
europepmc   +1 more source