A model for sensory adaptations of the visual system in squint. [PDF]
L. D. Pickwell
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
A heuristic mathematical model for the dynamics of sensory conflict and motion sickness [PDF]
The etiology of motion sickness is now usually explained in terms of a qualitatively formulated sensory conflict hypothesis. By consideration of the information processing task faced by the central nervous system in estimating body spatial orientation ...
Oman, C. M.
core +1 more source
Host-trailing satellite flight behaviour is associated with greater investment in peripheral visual sensory system in miltogrammine flies. [PDF]
Polidori C+4 more
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Microfluidic channel sensory system for electro-addressing cell location, determining confluency, and quantifying a general number of cells. [PDF]
Rapier CE+3 more
europepmc +1 more source
SENSORY INPUTS: FUEL FOR DIGITAL SYSTEMS [PDF]
J.W. Knutti, H.V. Allen
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Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Detection Theory Applied to the Absolute Sensitivity of Sensory Systems
E. G. J. Eijkman, A. J. H. Vendrik
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