Results 211 to 220 of about 23,457,740 (390)

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

The Suppressive Effect of the Motor System on the Sensory System in Patients With Tourette Syndrome. [PDF]

Front Neurol, 2020
Sun Y, Wei H, Lin Y, Wang Y.
europepmc   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Estrogens regulate early embryonic development of the olfactory sensory system via estrogen-responsive glia.

Development, 2022
Takesono A, Schirrmacher P, Scott A, Green JM, Lee O, Winter MJ, Kudoh T, Tyler CR.   +7 more
europepmc   +1 more source

Altered sensory system activity and connectivity patterns in adductor spasmodic dysphonia. [PDF]

Sci Rep, 2020
Mantel T, Dresel C, Welte M, Meindl T, Jochim A, Zimmer C, Haslinger B.   +6 more
europepmc   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Salmonid sensory system development is affected by climate change driven temperature increases. [PDF]

Sci Rep
Jones AE, O'Donnell MJ, Regish AM, Webb JF.   +3 more
europepmc   +1 more source

Modeling the Area of Interest for a Mobile Sensory System

, 2023
Szabó P, Galanda J, Muszka T.
europepmc   +1 more source

Erratum to : Comparative Studies on Characteristic Structures of Sensory and Motor Mechanisms in the Stomatognathic System of the Pangolin, Manis aurita (Mammalia)

, 1985

openalex   +2 more sources