Results 211 to 220 of about 335,786 (287)

The Safety, Pharmacokinetics, and Antiviral Activity of ABI‐4334, A Novel Next‐Generation Hepatitis B Capsid Assembly Modulator

open access: yesJournal of Viral Hepatitis, Volume 33, Issue 12, December 2026.
ABSTRACT Novel, well‐tolerated, short‐term therapeutics for chronic hepatitis B virus infection (cHBV) are needed. ABI‐4334 is a next‐generation capsid assembly modulator that targets the HBV core protein. The safety, tolerability, and pharmacokinetics of ABI‐4334 in healthy volunteers and participants with cHBV and antiviral effects in participants ...
Edward J. Gane   +11 more
wiley   +1 more source

Entomological surveillance of Trypanosoma cruzi vectors in Rio Grande do Norte, Brazil

open access: yesMedical and Veterinary Entomology, Volume 40, Issue 4, Page 1121-1129, December 2026.
Discontinuous entomological surveillance and persistent infestation by triatomines highlight the risk of Trypanosoma cruzi transmission. The diversity of triatomine species in the peridomicile shows the potential for colonization into the home. The wide distribution of Triatoma brasiliensis and Triatoma pseudomaculata accompanies high rates of ...
Letícia Mikardya Lima Sales   +10 more
wiley   +1 more source

Aryl Hydrocarbon Receptor Is Dispensable for the Early Transcriptional Response of Mouse Macrophages to Type I Interferon

open access: yesThe FASEB Journal, Volume 40, Issue 22, 30 November 2026.
ABSTRACT Type I interferon (IFN‐I) signaling is essential in the homeostasis and activation of immune cells, and macrophages play a central role in the IFN‐I system. Dysregulation leads to tissue damage and autoimmunity, and IFN‐I signaling needs to be tightly fine‐tuned.
Darawan Tabtim‐On, Elodie Segura
wiley   +1 more source

Sustained Ice Loss and Ice‐Shelf Flow Reorganization in the Carney‐Duncan Sector, Marie Byrd Land, West Antarctica (2010–2026)

open access: yesGeophysical Research Letters, Volume 53, Issue 22, 28 November 2026.
Abstract Small islands and ice rumples can regulate ice‐shelf flow, but conventional satellite altimetry poorly resolves their evolution. Here we use CryoSat‐2 SARIn swath altimetry to quantify surface‐elevation and volume changes over the Carney‐Duncan sector at the outer margin of West Antarctica's Getz Ice Shelf.
Byeong‐Hoon Kim   +6 more
wiley   +1 more source

Differentiated Rift Rupture and Apparent Northward Earthquake Ordering in Southern Tibet Revealed by the 2025 Mw 7.0 Dingri Earthquake and Its Preceding Events

open access: yesGeophysical Research Letters, Volume 53, Issue 21, 16 November 2026.
Abstract North–south‐trending rifts in southern Tibet accommodate active east–west extension, but how normal‐faulting rupture varies with rift development remains unclear. Here we use Synthetic Aperture Radar observations to investigate the 2025 Mw 7.0 Dingri earthquake in the southern Xainza–Dinggye rift.
Heng Luo, Liqing Jiao, Shuwen Dong
wiley   +1 more source

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