Results 201 to 210 of about 97,808,920 (303)

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

open access: yesiNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu   +5 more
wiley   +1 more source

Timeseries of multispectral and radar data and vegetation indices from Sentinel-1, Sentinel-2 and Landsat-8 at field scale. [PDF]

open access: yesData Brief
Frappart F   +7 more
europepmc   +1 more source

Tissue Clearing for Lymph Nodes: 3D Mapping of Nerves and the Immune Microenvironment

open access: yesiNew Medicine, EarlyView.
ABSTRACT Lymph nodes (LNs) are central hubs of adaptive immunity and key relay sites for metastatic tumour cells. However, conventional two‐dimensional histology samples only a small fraction of each node, potentially missing micrometastases and multifocal involvement while obscuring long‐range spatial relationships among tumour deposits, immune ...
Guang‐Hong Su   +7 more
wiley   +1 more source

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

open access: yesiNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin   +10 more
wiley   +1 more source

Challenging the Leukocyte‐Centric Model of Innate Immunity: The Emerging Role of Structural Cells in Immune Defense

open access: yesiNew Medicine, EarlyView.
Structural cells (endothelial, epithelial, neural, and muscle) actively participate in innate immunity as primary responders, challenging the traditional leukocyte‐centric paradigm and opening new therapeutic avenues for precision medicine. ABSTRACT Innate immunity has long been viewed as the domain of circulating mobile immune cells orchestrating ...
Sofya Urvanova, Suowen Xu
wiley   +1 more source

Optimized spectral indices for global vegetation and water mapping using Sentinel-2. [PDF]

open access: yesSci Rep
Chrysostomou C   +3 more
europepmc   +1 more source

Remote Sensing for Irrigation Water Management—The State of the Art and Prospects for Near‐Future Operations

open access: yesIrrigation and Drainage, EarlyView.
ABSTRACT A recent UN report describes many regions as facing ‘water bankruptcy,’ a condition in which available water resources can no longer meet existing demands. In practice, this means irrigation will likely bear the greatest burden of future water‐use reductions, a complicated and fraught decision to make given its critical role in food security ...
Wim G. M. Bastiaanssen   +30 more
wiley   +1 more source

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