Results 121 to 130 of about 96,831 (264)

Living Microbial Drugs

Chemistry – A European Journal, EarlyView.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik, Nazlıcan Tunç, Senem Şen, Urartu Özgür Şafak Şeker   +3 more
wiley   +1 more source

The Future of Foundation Machine Learning Potentials and DFT in Homogeneous Catalysis: Competition or Synergy?

Chemistry – A European Journal, EarlyView.
Machine‐learning potentials are increasingly taking on the exploratory tasks of homogeneous catalysis, enabling rapid conformer sampling and reaction‐space mapping. However, when selectivity depends on subtle electronic effects, electronic‐structure methods remain essential.
Maxime Ferrer, Julen Munarriz, Thijs Stuyver, Ruben Laplaza   +3 more
wiley   +1 more source

Precision Chemistry for Protein Lysine Modification

Chemistry – A European Journal, EarlyView.
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley   +1 more source

ANÁLISE DO EQUILÍBRIO FLUVIAL DO RIO JURUÁ COM DADOS DOS SATÉLITES SENTINEL 3-A E SENTINEL 3-B

A utilização da altimetria espacial, inicialmente desenvolvida para monitorar e mapear os oceanos, expandiu-se para incluir o monitoramento de águas continentais, oferecendo uma valiosa ferramenta no estudo da dinâmica fluvial. Esta pesquisa se concentra na análise do perfil longitudinal do Rio Juruá, um dos principais afluentes da Bacia Amazônica ...
Endi Samir Silva de Oliveira, Joecila Santos da Silva   +1 more
openaire   +2 more sources

From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

Cancer Nexus, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang, Chongchong Gao, Rui Jiang, Zijian Wu, Jian Bai   +4 more
wiley   +1 more source

Learning About and Learning From Sustainability Alliances: How Do SMEs Develop Dynamic Capabilities?

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines how small and medium‐sized enterprises (SMEs) develop sustainability capabilities by engaging in sustainability alliances. By combining perspectives on organisational learning theory and the dynamic capabilities framework, the research investigates how SMEs develop both networking and sustainability capabilities across ...
Raffaele Silvestri, Francesca Ceruti, Elisa Carloni, Anna Romagno   +3 more
wiley   +1 more source

How 1st‐Tier Suppliers Respond to Green Public Procurement Policies: An Empirical Analysis

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This article analyses how 1st‐tier suppliers to public organisations respond operationally to Green Public Procurement (GPP) policies. Through a multiple case study of 12 Italian firms operating in different sectors, we develop a classification of suppliers' responses, identifying two interrelated macro‐types: internal operations realignment ...
Antonio Cavallin Toscani, Andrea Vinelli
wiley   +1 more source

Establishment of pediatric reference ranges for circulating naïve and memory T and B cell subsets guided by the human immunophenotyping consortium standardization initiative: A large, single center U.S. experience

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
wiley   +1 more source

Explainable hybrid stacking ensemble method for hard rock pillar stability prediction and engineering applications

Deep Underground Science and Engineering, EarlyView.
This research proposes an interpretable hybrid stacking ensemble framework, optimized by the Sparrow Search Algorithm, to enhance hard rock pillar stability prediction. By integrating six machine learning models—k‐nearest neighbors, support vector machines, random forests, Gradient Boosting Decision Tree, eXtreme Gradient Boosting, and Light Gradient ...
Ning Wang, Guoyan Zhao, Meng Wang, Taraka Pattela   +3 more
wiley   +1 more source

Associations Between Microbial Depletion and Autonomic Dysregulation in Binge‐Eating Disorder

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective The interplay between the gut microbiome and autonomic nervous system remains unexplored in binge‐eating disorder (BED). We aimed to explore specific microbial alterations in BED and examine their potential association with cardiac vagal tone as a distinct bio‐behavioral phenotype.
Shuang Liang, Esben Strodl, Leanne Barron, Matthew Bambling, Luis Vitetta   +4 more
wiley   +1 more source