Results 41 to 50 of about 403,995 (295)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

The worsening impacts of land reclamation assessed with Sentinel-1: The Rize (Turkey) test case [PDF]

open access: yes, 2019
Massive amounts of land are being reclaimed to build airports, new cities, ports, and highways. Hundreds of kilometers are added each year, as coastlines are extended further out to the sea.
Althuwaynee   +50 more
core   +1 more source

Effect of Foot Orthoses on Midfoot Pain and the Volume of Bone Marrow Lesions in the Midfoot: A Randomized Mechanism of Action Study

open access: yesArthritis Care &Research, EarlyView.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain, and magnetic resonance imaging–confirmed midfoot BMLs ...
Jill Halstead   +4 more
wiley   +1 more source

Accuracy of Diagnostic Codes and Algorithms Used to Identify Rheumatoid Arthritis and Juvenile Idiopathic Arthritis in Administrative Claims and Electronic Health Records: Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective This systematic review aimed to assess the diagnostic accuracy of algorithms used to identify rheumatoid arthritis and juvenile idiopathic arthritis in electronic health records. Methods We searched Medline, Embase, and Cochrane Central Register for Controlled Trials databases and included studies that validated case definitions against a ...
Constanza Saka‐Herrán   +10 more
wiley   +1 more source

Shattered by War: The Huber Family [PDF]

open access: yes, 2013
The tale of Sergent Frederick Huber is relatively well known. The young man, fighting at the battle of Fair Oaks, was struck by three rounds, the final a bullet through his breast that quickly sapped him of his life.
Rudy, John M.
core   +1 more source

Oil Spill Detection Analyzing “Sentinel 2“ Satellite Images: A Persian Gulf Case Study [PDF]

open access: yes, 2018
Oil spills near exploitation areas and oil loading ports are often related to the ambitions of governments to get more oil market share and the negligence at the time of the loading in large tankers or ships.
GROPPI, DANIELE   +4 more
core   +1 more source

Chiral SURMOFs for Vibrational Circular Dichroism: Multiscale Modeling and Experimental Insights

open access: yesAdvanced Functional Materials, EarlyView.
The use of solid‐state vibrational circular dichroism (VCD) for MOFs is still somewhat unexplored, and in this work, it is shown that chiral surface‐anchored MOFs (SURMOFs) grown on CaF2 provide an excellent platform for VCD. Experimental results are validated through multiscale modeling, showing strong agreement across multiple spectroscopic ...
Ana C. Fingolo   +9 more
wiley   +1 more source

Immediate fall prevention: the missing key to a comprehensive solution for falling hazard in older adults

open access: yesFrontiers in Aging Neuroscience
The world is witnessing an unprecedented demographic shift due to increased life expectancy and declining birth rates. By 2050, 20% of the global population will be over 60, presenting significant challenges like a shortage of caregivers, maintaining ...
Khashayar Misaghian   +7 more
doaj   +1 more source

Monitoring Mega-Crown Leaf Turnover from Space

open access: yesRemote Sensing, 2020
Spatial and temporal patterns of tropical leaf renewal are poorly understood and poorly parameterized in modern Earth System Models due to lack of data.
Emma R. Bush   +6 more
doaj   +1 more source

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